气候变化领域集成服务门户(CCPortal): Physiological mechanisms of the impact of heat during pregnancy and the clinical implications: review of the evidence from an expert group meeting

CCPortal

DOI	10.1007/s00484-022-02301-6
	Physiological mechanisms of the impact of heat during pregnancy and the clinical implications: review of the evidence from an expert group meeting
	Samuels, Louisa; Nakstad, Britt; Roos, Nathalie; Bonell, Ana; Chersich, Matthew; Havenith, George; Luchters, Stanley; Day, Louise-Tina; Hirst, Jane E.; Singh, Tanya; Elliott-Sale, Kirsty; Hetem, Robyn; Part, Cherie; Sawry, Shobna; Le Roux, Jean; Kovats, Sari
发表日期	2022
ISSN	0020-7128
EISSN	1432-1254
起始页码	1505
结束页码	1513
卷号	66 期号:8
英文摘要	Many populations experience high seasonal temperatures. Pregnant women are considered vulnerable to extreme heat because ambient heat exposure has been linked to pregnancy complications including preterm birth and low birthweight. The physiological mechanisms that underpin these associations are poorly understood. We reviewed the existing research evidence to clarify the mechanisms that lead to adverse pregnancy outcomes in order to inform public health actions. A multi-disciplinary expert group met to review the existing evidence base and formulate a consensus regarding the physiological mechanisms that mediate the effect of high ambient temperature on pregnancy. A literature search was conducted in advance of the meeting to identify existing hypotheses and develop a series of questions and themes for discussion. Numerous hypotheses have been generated based on animal models and limited observational studies. There is growing evidence that pregnant women are able to appropriately thermoregulate; however, when exposed to extreme heat, there are a number of processes that may occur which could harm the mother or fetus including a reduction in placental blood flow, dehydration, and an inflammatory response that may trigger preterm birth. There is a lack of substantial evidence regarding the processes that cause heat exposure to harm pregnant women. Research is urgently needed to identify what causes the adverse outcomes in pregnancy related to high ambient temperatures so that the impact of climate change on pregnant women can be mitigated.
英文关键词	Heat stress; Clinical medicine; Pregnancy; Labour; Pregnant women; Foetus; Newborn
语种	英语
WOS研究方向	Biophysics ; Environmental Sciences ; Meteorology & Atmospheric Sciences ; Physiology
WOS类目	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000794070800001
来源期刊	INTERNATIONAL JOURNAL OF BIOMETEOROLOGY
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/281020
作者单位	Guy's & St Thomas' NHS Foundation Trust; University of Oslo; University of Botswana; Karolinska Institutet; University of London; London School of Hygiene & Tropical Medicine; University of London; London School of Hygiene & Tropical Medicine; University of Witwatersrand; Loughborough University; Aga Khan University; University of London; London School of Hygiene & Tropical Medicine; University of Oxford; University of Oxford; University of New South Wales Sydney; Nottingham Trent University; University of Witwatersrand
推荐引用方式 GB/T 7714	Samuels, Louisa,Nakstad, Britt,Roos, Nathalie,et al. Physiological mechanisms of the impact of heat during pregnancy and the clinical implications: review of the evidence from an expert group meeting[J],2022,66(8).
APA	Samuels, Louisa.,Nakstad, Britt.,Roos, Nathalie.,Bonell, Ana.,Chersich, Matthew.,...&Kovats, Sari.(2022).Physiological mechanisms of the impact of heat during pregnancy and the clinical implications: review of the evidence from an expert group meeting.INTERNATIONAL JOURNAL OF BIOMETEOROLOGY,66(8).
MLA	Samuels, Louisa,et al."Physiological mechanisms of the impact of heat during pregnancy and the clinical implications: review of the evidence from an expert group meeting".INTERNATIONAL JOURNAL OF BIOMETEOROLOGY 66.8(2022).