气候变化领域集成服务门户(CCPortal): Diversity and evolution of the animal virome

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DOI	10.1038/s41579-021-00665-x
	Diversity and evolution of the animal virome
	Harvey, Erin; Holmes, Edward C.
发表日期	2022
ISSN	1740-1526
EISSN	1740-1534
起始页码	321
结束页码	334
卷号	20 期号:6
英文摘要	The COVID-19 pandemic has given the study of virus evolution and ecology new relevance. Although viruses were first identified more than a century ago, we likely know less about their diversity than that of any other biological entity. Most documented animal viruses have been sampled from just two phyla - the Chordata and the Arthropoda - with a strong bias towards viruses that infect humans or animals of economic and social importance, often in association with strong disease phenotypes. Fortunately, the recent development of unbiased metagenomic next-generation sequencing is providing a richer view of the animal virome and shedding new light on virus evolution. In this Review, we explore our changing understanding of the diversity, composition and evolution of the animal virome. We outline the factors that determine the phylogenetic diversity and genomic structure of animal viruses on evolutionary timescales and show how this impacts assessment of the risk of disease emergence in the short term. We also describe the ongoing challenges in metagenomic analysis and outline key themes for future research. A central question is how major events in the evolutionary history of animals, such as the origin of the vertebrates and periodic mass extinction events, have shaped the diversity and evolution of the viruses they carry. In this Review, Harvey and Holmes explore our changing understanding of the structure, diversity and evolution of the animal virome. They also outline the factors that determine the phylogenetic diversity and genomic structure of animal viruses on evolutionary timescales and show how these impact assessment of the risk of disease emergence.
语种	英语
WOS研究方向	Microbiology
WOS类目	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000738411900001
来源期刊	NATURE REVIEWS MICROBIOLOGY
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/280797
作者单位	University of Sydney; University of Sydney; University of Sydney
推荐引用方式 GB/T 7714	Harvey, Erin,Holmes, Edward C.. Diversity and evolution of the animal virome[J],2022,20(6).
APA	Harvey, Erin,&Holmes, Edward C..(2022).Diversity and evolution of the animal virome.NATURE REVIEWS MICROBIOLOGY,20(6).
MLA	Harvey, Erin,et al."Diversity and evolution of the animal virome".NATURE REVIEWS MICROBIOLOGY 20.6(2022).