气候变化领域集成服务门户(CCPortal): Pathogen spillover driven by rapid changes in bat ecology

CCPortal

DOI	10.1038/s41586-022-05506-2
	Pathogen spillover driven by rapid changes in bat ecology
	Eby, Peggy; Peel, Alison J.; Hoegh, Andrew; Madden, Wyatt; Giles, John R.; Hudson, Peter J.; Plowright, Raina K.
发表日期	2023
ISSN	0028-0836
EISSN	1476-4687
起始页码	340
结束页码	+
卷号	613 期号:7943
英文摘要	During recent decades, pathogens that originated in bats have become an increasing public health concern. A major challenge is to identify how those pathogens spill over into human populations to generate a pandemic threat(1). Many correlational studies associate spillover with changes in land use or other anthropogenic stressors(2,3), although the mechanisms underlying the observed correlations have not been identified(4). One limitation is the lack of spatially and temporally explicit data on multiple spillovers, and on the connections among spillovers, reservoir host ecology and behaviour and viral dynamics. We present 25 years of data on land-use change, bat behaviour and spillover of Hendra virus from Pteropodid bats to horses in subtropical Australia. These data show that bats are responding to environmental change by persistently adopting behaviours that were previously transient responses to nutritional stress. Interactions between land-use change and climate now lead to persistent bat residency in agricultural areas, where periodic food shortages drive clusters of spillovers. Pulses of winter flowering of trees in remnant forests appeared to prevent spillover. We developed integrative Bayesian network models based on these phenomena that accurately predicted the presence or absence of clusters of spillovers in each of the 25 years. Our long-term study identifies the mechanistic connections between habitat loss, climate and increased spillover risk. It provides a framework for examining causes of bat virus spillover and for developing ecological countermeasures to prevent pandemics.
语种	英语
WOS研究方向	Multidisciplinary Sciences
WOS类目	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000901942700001
来源期刊	NATURE
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/280556
作者单位	University of New South Wales Sydney; Griffith University; Montana State University System; Montana State University Bozeman; Montana State University System; Montana State University Bozeman; Johns Hopkins University; Johns Hopkins Bloomberg School of Public Health; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Cornell University; Emory University; Rollins School Public Health; University of Washington; University of Washington Seattle; Institute for Health Metrics & Evaluation
推荐引用方式 GB/T 7714	Eby, Peggy,Peel, Alison J.,Hoegh, Andrew,et al. Pathogen spillover driven by rapid changes in bat ecology[J],2023,613(7943).
APA	Eby, Peggy.,Peel, Alison J..,Hoegh, Andrew.,Madden, Wyatt.,Giles, John R..,...&Plowright, Raina K..(2023).Pathogen spillover driven by rapid changes in bat ecology.NATURE,613(7943).
MLA	Eby, Peggy,et al."Pathogen spillover driven by rapid changes in bat ecology".NATURE 613.7943(2023).