气候变化领域集成服务门户(CCPortal): Genomic Insights ofCryobacteriumIsolated From Ice Core Reveal Genome Dynamics for Adaptation in Glacier

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DOI	10.3389/fmicb.2020.01530
	Genomic Insights ofCryobacteriumIsolated From Ice Core Reveal Genome Dynamics for Adaptation in Glacier
	Liu, Yongqin; Shen, Liang; Zeng, Yonghui; Xing, Tingting; Xu, Baiqing; Wang, Ninglian
通讯作者	Liu, YQ (通讯作者)
发表日期	2020
ISSN	1664-302X
卷号	11
英文摘要	Glacier is the dominant cold habitat in terrestrial environments, providing a model ecosystem to explore extremophilic strategies and study early lives on Earth. The dominant form of life in glaciers is bacteria. However, little is known about past evolutionary processes that bacteria underwent during adaptation to the cryosphere and the connection of their genomic traits to environmental stressors. Aiming to test the hypothesis that bacterial genomic content and dynamics are driven by glacial environmental stressors, we compared genomes of 21 psychrophilicCryobacteriumstrains, including 14 that we isolated from three Tibetan ice cores, to their mesophilic counterparts from the same family Microbacteriaceae of Actinobacteria. The results show that psychrophilicCryobacteriumunderwent more dynamic changes in genome content, and their genomes have a significantly higher number of genes involved in stress response, motility, and chemotaxis than their mesophilic counterparts (P< 0.05). The phylogenetic birth-and-death model imposed on the phylogenomic tree indicates a vast surge in recent common ancestor of psychrophilicCryobacterium(gained the greatest number of genes by 1,168) after the division of the mesophilic strainCryobacterium mesophilum. The expansion in genome content brought in key genes primarily of the categories cofactors, vitamins, prosthetic groups, pigments, monosaccharides metabolism, and membrane transport. The amino acid substitution rates of psychrophilicCryobacteriumstrains are two orders of magnitude lower than those in mesophilic strains. However, no significantly higher number of cold shock genes was found in psychrophilicCryobacteriumstrains, indicating that multi-copy is not a key factor for cold adaptation in the family Microbacteriaceae, although cold shock genes are indispensable for psychrophiles. Extensive gene acquisition and low amino acid substitution rate might be the strategies of psychrophilicCryobacteriumto resist low temperature, oligotrophy, and high UV radiation on glaciers. The exploration of genome evolution and survival strategies of psychrophilicCryobacteriumdeepens our understanding of bacterial cold adaptation.
关键词	SP-NOV.PSYCHROTOLERANT BACTERIUM ALTITUDE ADAPTATION SURVIVAL STRATEGIES RAPID ANNOTATION GEN. NOV.SEQUENCE PSYCHROPHILE MECHANISMS DIVERSITY
英文关键词	glacier; Cryobacterium; genomic; evolutionary processes; cold adaptation
语种	英语
WOS研究方向	Microbiology
WOS类目	Microbiology
WOS记录号	WOS:000556836300001
来源期刊	FRONTIERS IN MICROBIOLOGY
来源机构	中国科学院青藏高原研究所
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/260024
推荐引用方式 GB/T 7714	Liu, Yongqin,Shen, Liang,Zeng, Yonghui,et al. Genomic Insights ofCryobacteriumIsolated From Ice Core Reveal Genome Dynamics for Adaptation in Glacier[J]. 中国科学院青藏高原研究所,2020,11.
APA	Liu, Yongqin,Shen, Liang,Zeng, Yonghui,Xing, Tingting,Xu, Baiqing,&Wang, Ninglian.(2020).Genomic Insights ofCryobacteriumIsolated From Ice Core Reveal Genome Dynamics for Adaptation in Glacier.FRONTIERS IN MICROBIOLOGY,11.
MLA	Liu, Yongqin,et al."Genomic Insights ofCryobacteriumIsolated From Ice Core Reveal Genome Dynamics for Adaptation in Glacier".FRONTIERS IN MICROBIOLOGY 11(2020).