气候变化领域集成服务门户(CCPortal): A late Middle Pleistocene Denisovan mandible from the Tibetan Plateau

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DOI	10.1038/s41586-019-1139-x
	A late Middle Pleistocene Denisovan mandible from the Tibetan Plateau
	Chen, Fahu; Welker, Frido; Shen, Chuan-Chou; Bailey, Shara E.; Bergmann, Inga; Davis, Simon; Xia, Huan; Wang, Hui; Fischer, Roman; Freidline, Sarah E.; Yu, Tsai-Luen; Skinner, Matthew M.; Stelzer, Stefanie; Dong, Guangrong; Fu, Qiaomei; Dong, Guanghui; Wang, Jian; Zhang, Dongju; Hublin, Jean-Jacques
通讯作者	Chen, FH (通讯作者)
发表日期	2019
ISSN	0028-0836
EISSN	1476-4687
起始页码	409
结束页码	+
卷号	569 期号:7756
英文摘要	Denisovans are members of a hominin group who are currently only known directly from fragmentary fossils, the genomes of which have been studied from a single site, Denisova Cave(1-3) in Siberia. They are also known indirectly from their genetic legacy through gene flow into several low-altitude East Asian populations(4,5) and high-altitude modern Tibetans(6). The lack of morphologically informative Denisovan fossils hinders our ability to connect geographically and temporally dispersed fossil hominins from Asia and to understand in a coherent manner their relation to recent Asian populations. This includes understanding the genetic adaptation of humans to the high-altitude Tibetan Plateau(7,8), which was inherited from the Denisovans. Here we report a Denisovan mandible, identified by ancient protein analysis(9,10), found on the Tibetan Plateau in Baishiya Karst Cave, Xiahe, Gansu, China. We determine the mandible to be at least 160 thousand years old through U-series dating of an adhering carbonate matrix. The Xiahe specimen provides direct evidence of the Denisovans outside the Altai Mountains and its analysis unique insights into Denisovan mandibular and dental morphology. Our results indicate that archaic hominins occupied the Tibetan Plateau in the Middle Pleistocene epoch and successfully adapted to high-altitude hypoxic environments long before the regional arrival of modern Homo sapiens.
关键词	PERMANENT HUMAN OCCUPATION GENOME SEQUENCE HIGH-PRECISION HOMININ CAVE BONE DEAMIDATION MORPHOLOGY GLUTAMINE ANCESTRY
语种	英语
WOS研究方向	Science & Technology - Other Topics
WOS类目	Multidisciplinary Sciences
WOS记录号	WOS:000468123700039
来源期刊	NATURE
来源机构	中国科学院青藏高原研究所
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/259656
推荐引用方式 GB/T 7714	Chen, Fahu,Welker, Frido,Shen, Chuan-Chou,et al. A late Middle Pleistocene Denisovan mandible from the Tibetan Plateau[J]. 中国科学院青藏高原研究所,2019,569(7756).
APA	Chen, Fahu.,Welker, Frido.,Shen, Chuan-Chou.,Bailey, Shara E..,Bergmann, Inga.,...&Hublin, Jean-Jacques.(2019).A late Middle Pleistocene Denisovan mandible from the Tibetan Plateau.NATURE,569(7756).
MLA	Chen, Fahu,et al."A late Middle Pleistocene Denisovan mandible from the Tibetan Plateau".NATURE 569.7756(2019).