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DOI	10.1145/3291801.3291840
	AtNAGNAG: a comprehensive database for NAGNAG alternative splicing in Arabidopsis thaliana
	Zhang, Qinglei; Zhang, Qinran; Li, Shuzhang; Ye, Jiazhen; Tang, Wenhao; Yin, Meng; Wang, Keyi; Wang, Kai; Shi, Chuanhong; Wang, Chong; Fan, Hao; Sun, Xiaoyong; Sablok, Gaurav; Song, Wuli; Wang, Bingbing; Zhang, Gengxin
通讯作者	Sun, XY (通讯作者)
发表日期	2018
起始页码	33
结束页码	37
英文摘要	NAGNAG alternative splicing is widely present in animal genomes. In plants, there has been little large-scale exploration of NAGNAG splicing, even in model plants such as Arabidopsis thaliana. To address this, here we describe the first database of NAGNAG motifs and their expression ratios between two splicing sites in A. thaliana. Using 435 RNA-seq datasets, we systematically identified and quantified 1,890 unique NAGNAG motifs as well as the variation of expression ratio between two splicing sites from six tissues, including 200 motifs with two novel splicing sites and 1,208 motifs containing one novel splicing site. Using this database, it is now possible to browse, search, visualize and download Arabidopsis NAGNAG motifs. The collected information can also be used to retrieve the related tissue-specific transcript and amino acid information. The database largely expands our knowledge about NAGNAG events. Placing these data in a unified browsing platform should enable high throughput functional validation of the identified NAGNAG events and understand the regulatory role of NAGNAG splicing motifs through the variation of expression ratios. Database URL: http://deepbiology.cn/nagnag.
关键词	GENOME-WIDE WIDESPREAD LANDSCAPE EVENTS PLANTS
英文关键词	NAGNAG alternative splicing; tissue-specific; database; arabidopsis; RNA-Seq
语种	英语
WOS研究方向	Computer Science
WOS类目	Computer Science, Artificial Intelligence ; Computer Science, Information Systems ; Computer Science, Theory & Methods
WOS记录号	WOS:000461579000007
来源期刊	PROCEEDINGS OF THE 2018 2ND INTERNATIONAL CONFERENCE ON BIG DATA RESEARCH (ICBDR 2018)
来源机构	中国科学院青藏高原研究所
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/259239
推荐引用方式 GB/T 7714	Zhang, Qinglei,Zhang, Qinran,Li, Shuzhang,et al. AtNAGNAG: a comprehensive database for NAGNAG alternative splicing in Arabidopsis thaliana[J]. 中国科学院青藏高原研究所,2018.
APA	Zhang, Qinglei.,Zhang, Qinran.,Li, Shuzhang.,Ye, Jiazhen.,Tang, Wenhao.,...&Zhang, Gengxin.(2018).AtNAGNAG: a comprehensive database for NAGNAG alternative splicing in Arabidopsis thaliana.PROCEEDINGS OF THE 2018 2ND INTERNATIONAL CONFERENCE ON BIG DATA RESEARCH (ICBDR 2018).
MLA	Zhang, Qinglei,et al."AtNAGNAG: a comprehensive database for NAGNAG alternative splicing in Arabidopsis thaliana".PROCEEDINGS OF THE 2018 2ND INTERNATIONAL CONFERENCE ON BIG DATA RESEARCH (ICBDR 2018) (2018).