气候变化领域集成服务门户(CCPortal): Experimental manipulation of microbiota reduces host thermal tolerance and fitness under heat stress in a vertebrate ectotherm

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DOI	10.1038/s41559-022-01686-2
	Experimental manipulation of microbiota reduces host thermal tolerance and fitness under heat stress in a vertebrate ectotherm
	Fontaine S.S.; Mineo P.M.; Kohl K.D.
发表日期	2022
ISSN	2397-334X
起始页码	405
结束页码	417
卷号	6 期号:4
英文摘要	Identifying factors that influence how ectothermic animals respond physiologically to changing temperatures is of high importance given current threats of global climate change. Host-associated microbial communities impact animal physiology and have been shown to influence host thermal tolerance in invertebrate systems. However, the role of commensal microbiota in the thermal tolerance of ectothermic vertebrates is unknown. Here we show that experimentally manipulating the tadpole microbiome through environmental water sterilization reduces the host’s acute thermal tolerance to both heat and cold, alters the thermal sensitivity of locomotor performance, and reduces animal survival under prolonged heat stress. We show that these tadpoles have reduced activities of mitochondrial enzymes and altered metabolic rates compared with tadpoles colonized with unmanipulated microbiota, which could underlie differences in thermal phenotypes. These results demonstrate a strong link between the microbiota of an ectothermic vertebrate and the host’s thermal tolerance, performance and fitness. It may therefore be important to consider host-associated microbial communities when predicting species’ responses to climate change. ? 2022, The Author(s), under exclusive licence to Springer Nature Limited.
语种	英语
scopus关键词	animal; climate change; cold; heat shock response; larva; microflora; vertebrate; Animals; Climate Change; Cold Temperature; Heat-Shock Response; Larva; Microbiota; Vertebrates
来源期刊	Nature Ecology & Evolution
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/257098
作者单位	Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, United States; Department of Biology, Elmhurst University, Elmhurst, IL, United States
推荐引用方式 GB/T 7714	Fontaine S.S.,Mineo P.M.,Kohl K.D.. Experimental manipulation of microbiota reduces host thermal tolerance and fitness under heat stress in a vertebrate ectotherm[J],2022,6(4).
APA	Fontaine S.S.,Mineo P.M.,&Kohl K.D..(2022).Experimental manipulation of microbiota reduces host thermal tolerance and fitness under heat stress in a vertebrate ectotherm.Nature Ecology & Evolution,6(4).
MLA	Fontaine S.S.,et al."Experimental manipulation of microbiota reduces host thermal tolerance and fitness under heat stress in a vertebrate ectotherm".Nature Ecology & Evolution 6.4(2022).