气候变化领域集成服务门户(CCPortal): Towards an ecosystem model of infectious disease

CCPortal

DOI	10.1038/s41559-021-01454-8
	Towards an ecosystem model of infectious disease
	Hassell J.M.; Newbold T.; Dobson A.P.; Linton Y.-M.; Franklinos L.H.V.; Zimmerman D.; Pagenkopp Lohan K.M.
发表日期	2021
ISSN	2397-334X
起始页码	907
结束页码	918
卷号	5 期号:7
英文摘要	Increasingly intimate associations between human society and the natural environment are driving the emergence of novel pathogens, with devastating consequences for humans and animals alike. Prior to emergence, these pathogens exist within complex ecological systems that are characterized by trophic interactions between parasites, their hosts and the environment. Predicting how disturbance to these ecological systems places people and animals at risk from emerging pathogens—and the best ways to manage this—remains a significant challenge. Predictive systems ecology models are powerful tools for the reconstruction of ecosystem function but have yet to be considered for modelling infectious disease. Part of this stems from a mistaken tendency to forget about the role that pathogens play in structuring the abundance and interactions of the free-living species favoured by systems ecologists. Here, we explore how developing and applying these more complete systems ecology models at a landscape scale would greatly enhance our understanding of the reciprocal interactions between parasites, pathogens and the environment, placing zoonoses in an ecological context, while identifying key variables and simplifying assumptions that underly pathogen host switching and animal-to-human spillover risk. As well as transforming our understanding of disease ecology, this would also allow us to better direct resources in preparation for future pandemics. ? 2021, This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply.
语种	英语
scopus关键词	animal; communicable disease; ecosystem; human; zoonosis; Animals; Communicable Diseases; Ecosystem; Humans; Zoonoses
来源期刊	Nature Ecology & Evolution
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/256914
作者单位	Global Health Program, Smithsonian Conservation Biology Institute, Washington, DC, United States; Department of Epidemiology of Microbial Disease, Yale School of Public Health, New Haven, CT, United States; Centre for Biodiversity & Environment Research (CBER), Department of Genetics, Evolution and Environment, University College London, London, United Kingdom; Department of Ecology & Evolutionary Biology, Princeton University, Princeton, NJ, United States; Santa Fe Institute, Santa Fe, NM, United States; Walter Reed Biosystematics Unit (WRBU), Smithsonian Institution Museum Support Center, Suitland, MD, United States; Department of Entomology, Smithsonian National Museum of Natural History, Washington, DC, United States; Walter Reed Army Institute of Research (WRAIR), Silver Spring, MD, United States; Marine Disease Ecology Laboratory, Smithsonian Environmental Research Center, Edgewater, MD, United States
推荐引用方式 GB/T 7714	Hassell J.M.,Newbold T.,Dobson A.P.,et al. Towards an ecosystem model of infectious disease[J],2021,5(7).
APA	Hassell J.M..,Newbold T..,Dobson A.P..,Linton Y.-M..,Franklinos L.H.V..,...&Pagenkopp Lohan K.M..(2021).Towards an ecosystem model of infectious disease.Nature Ecology & Evolution,5(7).
MLA	Hassell J.M.,et al."Towards an ecosystem model of infectious disease".Nature Ecology & Evolution 5.7(2021).