气候变化领域集成服务门户(CCPortal): Plasmids do not consistently stabilize cooperation across bacteria but may promote broad pathogen host-range

CCPortal

DOI	10.1038/s41559-021-01573-2
	Plasmids do not consistently stabilize cooperation across bacteria but may promote broad pathogen host-range
	Dewar A.E.; Thomas J.L.; Scott T.W.; Wild G.; Griffin A.S.; West S.A.; Ghoul M.
发表日期	2021
ISSN	2397-334X
起始页码	1624
结束页码	1636
卷号	5 期号:12
英文摘要	Horizontal gene transfer via plasmids could favour cooperation in bacteria, because transfer of a cooperative gene turns non-cooperative cheats into cooperators. This hypothesis has received support from theoretical, genomic and experimental analyses. By contrast, we show here, with a comparative analysis across 51 diverse species, that genes for extracellular proteins, which are likely to act as cooperative ‘public goods’, were not more likely to be carried on either: (1) plasmids compared to chromosomes; or (2) plasmids that transfer at higher rates. Our results were supported by theoretical modelling which showed that, while horizontal gene transfer can help cooperative genes initially invade a population, it has less influence on the longer-term maintenance of cooperation. Instead, we found that genes for extracellular proteins were more likely to be on plasmids when they coded for pathogenic virulence traits, in pathogenic bacteria with a broad host-range. ? 2021, The Author(s), under exclusive licence to Springer Nature Limited.
语种	英语
scopus关键词	bacterium; genetics; horizontal gene transfer; host range; plasmid; Bacteria; Gene Transfer, Horizontal; Host Specificity; Plasmids
来源期刊	Nature Ecology & Evolution
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/256805
作者单位	Department of Zoology, University of Oxford, Oxford, United Kingdom; Department of Applied Mathematics, University of Western Ontario, London, ON, Canada
推荐引用方式 GB/T 7714	Dewar A.E.,Thomas J.L.,Scott T.W.,et al. Plasmids do not consistently stabilize cooperation across bacteria but may promote broad pathogen host-range[J],2021,5(12).
APA	Dewar A.E..,Thomas J.L..,Scott T.W..,Wild G..,Griffin A.S..,...&Ghoul M..(2021).Plasmids do not consistently stabilize cooperation across bacteria but may promote broad pathogen host-range.Nature Ecology & Evolution,5(12).
MLA	Dewar A.E.,et al."Plasmids do not consistently stabilize cooperation across bacteria but may promote broad pathogen host-range".Nature Ecology & Evolution 5.12(2021).