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DOI	10.1016/j.msec.2021.112013
	Recent advances in bioprinting technologies for engineering hepatic tissue
	Agarwal, Tarun; Banerjee, Dishary; Konwarh, Rocktotpal; Esworthy, Timothy; Kumari, Jyoti; Onesto, Valentina; Das, Prativa; Lee, Bae Hoon; Wagener, Frank A. D. T. G.; Makvandi, Pooyan; Mattoli, Virgilio; Ghosh, Sudip Kumar; Maiti, Tapas Kumar; Zhang, Lijie Grace; Ozbolat, Ibrahim T.
通讯作者	Maiti, TK (通讯作者)，Indian Inst Technol Kharagpur, Dept Biotechnol, Kharagpur 721302, W Bengal, India. ; Ozbolat, IT (通讯作者)，Penn State Univ, Dept Engn Sci & Mech, 227 Hammond Bldg, University Pk, PA 16802 USA. ; Ozbolat, IT (通讯作者)，Penn State Univ, Huck Inst Life Sci, University Pk, PA 16802 USA. ; Zhang, LG (通讯作者)，George Washington Univ, Dept Mech & Aerosp Engn, Washington, DC 20052 USA. ; Ozbolat, IT (通讯作者)，Penn State Univ, Biomed Engn Dept, University Pk, PA 16802 USA. ; Ozbolat, IT (通讯作者)，Penn State Univ, Mat Res Inst, University Pk, PA 16802 USA. ; Ozbolat, IT (通讯作者)，Penn State Coll Med, Dept Neurosurg, Hershey, PA 17033 USA.
发表日期	2021
ISSN	0928-4931
EISSN	1873-0191
卷号	123
英文摘要	In the sphere of liver tissue engineering (LTE), 3D bioprinting has emerged as an effective technology to mimic the complex in vivo hepatic microenvironment, enabling the development of functional 3D constructs with potential application in the healthcare and diagnostic sector. This review gears off with a note on the liver?s microscopic 3D architecture and pathologies linked to liver injury. The write-up is then directed towards unmasking recent advancements and prospects of bioprinting for recapitulating 3D hepatic structure and function. The article further introduces available stem cell opportunities and different strategies for their directed differentiation towards various hepatic stem cell types, including hepatocytes, hepatic sinusoidal endothelial cells, stellate cells, and Kupffer cells. Another thrust of the article is on understanding the dynamic interplay of different hepatic cells with various microenvironmental cues, which is crucial for controlling differentiation, maturation, and maintenance of functional hepatic cell phenotype. On a concluding note, various critical issues and future research direction towards clinical translation of bioprinted hepatic constructs are discussed.
英文关键词	Liver tissue engineering; Bioprinting; Stem cell differentiation; Microenvironmental cues
语种	英语
WOS研究方向	Materials Science
WOS类目	Materials Science, Biomaterials
WOS记录号	WOS:000637208400005
来源期刊	MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
来源机构	中国科学院西北生态环境资源研究院
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/255204
作者单位	[Agarwal, Tarun; Ghosh, Sudip Kumar; Maiti, Tapas Kumar] Indian Inst Technol Kharagpur, Dept Biotechnol, Kharagpur 721302, W Bengal, India; [Banerjee, Dishary; Ozbolat, Ibrahim T.] Penn State Univ, Dept Engn Sci & Mech, 227 Hammond Bldg, University Pk, PA 16802 USA; [Banerjee, Dishary; Ozbolat, Ibrahim T.] Penn State Univ, Huck Inst Life Sci, University Pk, PA 16802 USA; [Konwarh, Rocktotpal] Uniglobe Sci Pvt Ltd, Div Nanobiomat & Nanomed, 7-9 Vast Kunj, New Delhi 110070, India; [Esworthy, Timothy; Zhang, Lijie Grace] George Washington Univ, Dept Mech & Aerosp Engn, Washington, DC 20052 USA; [Kumari, Jyoti] Radboud Univ Nijmegen, Inst Mol & Mat, Heyendaalseweg 135, NL-6525 AJ Nijmegen, Netherlands; [Kumari, Jyoti; Wagener, Frank A. D. T. G.] Radboud Univ Nijmegen, Med Ctr, Dept Dent, Sect Orthodont & Craniofacial Biol, Nijmegen, Netherlands; [Onesto, Valentina] Natl Res Council CNR NANOTEC, Inst Nanotechnol, Campus Ecotekne,Via Monteroni, I-73100 Lecce, Italy; [Das, Prativa] Nanyang Technol Univ, NTU Nort...
推荐引用方式 GB/T 7714	Agarwal, Tarun,Banerjee, Dishary,Konwarh, Rocktotpal,et al. Recent advances in bioprinting technologies for engineering hepatic tissue[J]. 中国科学院西北生态环境资源研究院,2021,123.
APA	Agarwal, Tarun.,Banerjee, Dishary.,Konwarh, Rocktotpal.,Esworthy, Timothy.,Kumari, Jyoti.,...&Ozbolat, Ibrahim T..(2021).Recent advances in bioprinting technologies for engineering hepatic tissue.MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,123.
MLA	Agarwal, Tarun,et al."Recent advances in bioprinting technologies for engineering hepatic tissue".MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 123(2021).