气候变化领域集成服务门户(CCPortal): Two new polycyclic polyprenylated acylphloroglucinols derivatives from Hypericum acmosepalum

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DOI	10.1080/10286020.2021.1880395
	Two new polycyclic polyprenylated acylphloroglucinols derivatives from Hypericum acmosepalum
	Suo, Xin-yue; Shi, Meng-jiao; Dang, Jun; Yue, Hui-lan; Tao, Yan-duo; Zhen, Bo; Wang, Jia-jia; Wang, Xue; Sun, Hao-ran; Sun, Hua; Qiang, Gui-fen; Ji, Teng-fei; Liu, Bo
通讯作者	Ji, TF (通讯作者)，Chinese Acad Med Sci & Peking Union Med Coll, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China. ; Liu, B (通讯作者)，Shenyang Med Coll, Sch Pharm, Shenyang 110034, Peoples R China.
发表日期	2021
ISSN	1028-6020
EISSN	1477-2213
起始页码	1068
结束页码	1076
卷号	23 期号:11
英文摘要	Polycyclic polyprenylated acylphloroglucinols (PPAPs) were mainly obtained from the plants of Hypericum genus of Guttiferae family, and possessed intriguing chemical structures and appealing biological activities. Two new PPAPs derivatives, hyperacmosin C (1) and hyperacmosin D (2) were isolated from H. acmosepalum. Their structures were established by NMR, HREIMS, and experimental electronic circular dichroism spectra. Besides, compound 1 showed significant hepatoprotective activity at 10 mu M against paracetamol-induced HepG2 cell damage and compound 2 could moderately increase the relative glucose consumption.
英文关键词	PPAPs; Hypericum acmosepalum; ECD; hepatoprotective activity; relative glucose consumption
语种	英语
WOS研究方向	Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
WOS类目	Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号	WOS:000616835300001
来源期刊	JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
来源机构	中国科学院西北生态环境资源研究院
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/254876
作者单位	[Suo, Xin-yue; Shi, Meng-jiao; Zhen, Bo; Wang, Jia-jia; Wang, Xue; Sun, Hao-ran; Sun, Hua; Qiang, Gui-fen; Ji, Teng-fei] Chinese Acad Med Sci & Peking Union Med Coll, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China; [Dang, Jun; Yue, Hui-lan; Tao, Yan-duo; Ji, Teng-fei] Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining 810008, Peoples R China; [Liu, Bo] Shenyang Med Coll, Sch Pharm, Shenyang 110034, Peoples R China
推荐引用方式 GB/T 7714	Suo, Xin-yue,Shi, Meng-jiao,Dang, Jun,et al. Two new polycyclic polyprenylated acylphloroglucinols derivatives from Hypericum acmosepalum[J]. 中国科学院西北生态环境资源研究院,2021,23(11).
APA	Suo, Xin-yue.,Shi, Meng-jiao.,Dang, Jun.,Yue, Hui-lan.,Tao, Yan-duo.,...&Liu, Bo.(2021).Two new polycyclic polyprenylated acylphloroglucinols derivatives from Hypericum acmosepalum.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,23(11).
MLA	Suo, Xin-yue,et al."Two new polycyclic polyprenylated acylphloroglucinols derivatives from Hypericum acmosepalum".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 23.11(2021).