气候变化领域集成服务门户(CCPortal): Comparison of the community-acquired pneumonia and COVID-19 at the early stage: findings from two cohort studies

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DOI	10.21037/apm-21-2006
	Comparison of the community-acquired pneumonia and COVID-19 at the early stage: findings from two cohort studies
	Zhang, Liting; Li, Yonghong; Zhou, Jianye; Li, Junfeng; Tong, Chongxiang; Cai, Jing; Yang, Zengwei; Li, Shuyan; Zhu, Jinhong; Zhao, Meie; Bai, Zhongtian; Xie, Xiaodong; Chen, Tuo
通讯作者	Chen, T (通讯作者)，Chinese Acad Sci, State Key Lab Cryospher Sci, Northwest Inst Ecoenvironm & Resources, Lanzhou 730000, Peoples R China. ; Chen, T (通讯作者)，Univ Chinese Acad Sci, Beijing 100049, Peoples R China. ; Xie, XD (通讯作者)，Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drug Gansu Prov, Lanzhou 730000, Peoples R China.
发表日期	2021
ISSN	2224-5820
EISSN	2224-5839
起始页码	9572
结束页码	9582
卷号	10 期号:9
英文摘要	Background: The current focus is largely on whole course medical management of coronavirus disease-19 (COVID-19) with real-time polymerase chain reaction (RT-PCR) and radiological features, while the mild cases are usually missed. Thus, combination of multiple diagnostic methods is urgent to understand COVID-19 fully and to monitor the progression of COVID-19. Methods: laboratory variables of 40 mild COVID-19 patients, 30 patients with community-acquired pneumonia (CAP) and 32 healthy individuals were analyzed by principal component analysis (PCA), Kruskal test, Procrustes test, the vegan package in R, CCA package and receiver operating characteristic to investigate the characteristics of the laboratory variables and their relationships in COVID-19. Results: The correlations between the laboratory variables presented a variety of intricate linkages in the COVID-19 group compared with the healthy group and CAP patient group. The prediction probability of the combination of lymphocyte count (LY), eosinophil (EO) and platelets (PLT) was 0.847, 0.854 for the combination of lactate (LDH), creatine kinase isoenzyme (CK-MB), and C-reactive protein (CRP), 0.740 for the combination of EO, white blood cell count (WBC) and neutrophil count (NEUT) and 0.872 for the combination of CK-MB and P. Conclusions: The correlations between the laboratory variables in the COVID-19 group could be a unique characteristic showing promise as a method for COVID-19 prediction and monitoring progression of COVID-19 infection.
英文关键词	Combination; correlation; coronavirus disease-19 (COVID-19); diagnosis; laboratory variables
语种	英语
WOS研究方向	Health Care Sciences & Services
WOS类目	Health Care Sciences & Services
WOS记录号	WOS:000700933800001
来源期刊	ANNALS OF PALLIATIVE MEDICINE
来源机构	中国科学院西北生态环境资源研究院
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/254844
作者单位	[Zhang, Liting; Chen, Tuo] Chinese Acad Sci, State Key Lab Cryospher Sci, Northwest Inst Ecoenvironm & Resources, Lanzhou 730000, Peoples R China; [Zhang, Liting; Chen, Tuo] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Zhang, Liting; Li, Junfeng] Lanzhou Univ, Dept Infect Dis, First Hosp, Lanzhou, Peoples R China; [Li, Yonghong; Xie, Xiaodong] Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drug Gansu Prov, Lanzhou 730000, Peoples R China; [Li, Yonghong; Xie, Xiaodong] Gansu Prov Hosp, NHC Key Lab Diag & Therapy Gastrointestinal Tumor, Lanzhou, Peoples R China; [Zhou, Jianye] Northwest Minzu Univ, Biomed Res Ctr, Key Lab Oral Dis Gansu Prov, Key Lab Stomatol State Ethn Affairs Commiss, Lanzhou, Peoples R China; [Tong, Chongxiang; Cai, Jing; Yang, Zengwei] Pulm Hosp Lanzhou, Clin Lab, Lanzhou, Peoples R China; [Li, Shuyan] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou, Peoples R China; [Zhu, Jinhong; Bai, Zhongtian] Lanzhou Univ, Clin Lab, First Hosp, Lanzhou, Peoples R China;...
推荐引用方式 GB/T 7714	Zhang, Liting,Li, Yonghong,Zhou, Jianye,et al. Comparison of the community-acquired pneumonia and COVID-19 at the early stage: findings from two cohort studies[J]. 中国科学院西北生态环境资源研究院,2021,10(9).
APA	Zhang, Liting.,Li, Yonghong.,Zhou, Jianye.,Li, Junfeng.,Tong, Chongxiang.,...&Chen, Tuo.(2021).Comparison of the community-acquired pneumonia and COVID-19 at the early stage: findings from two cohort studies.ANNALS OF PALLIATIVE MEDICINE,10(9).
MLA	Zhang, Liting,et al."Comparison of the community-acquired pneumonia and COVID-19 at the early stage: findings from two cohort studies".ANNALS OF PALLIATIVE MEDICINE 10.9(2021).