气候变化领域集成服务门户(CCPortal): Heavy metals bioaccumulation and subsequent multiple biomarkers based appraisal of toxicity in the critically endangered Tor putitora

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DOI	10.1016/j.ecoenv.2021.113032
	Heavy metals bioaccumulation and subsequent multiple biomarkers based appraisal of toxicity in the critically endangered Tor putitora
	Ullah, Sana; Li, Zhongqiu; Hassan, Said; Ahmad, Shahid; Guo, Xinle; Wanghe, Kunyuan; Nabi, Ghulam
通讯作者	Li, ZQ (通讯作者)，Nanjing Univ, Sch Life Sci, Anim Behav & Conservat Lab, Nanjing 210023, Jiangsu, Peoples R China. ; Nabi, G (通讯作者)，Hebei Normal Univ, Coll Life Sci, Key Lab Anim Physiol Biochem & Mol Biol Hebei Pro, Shijiazhuang 050010, Hebei, Peoples R China. ; Wanghe, K (通讯作者)，Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, Qinghai Prov Key Lab Anim Ecol Genom, 23th Xinning Rd, Xining 810008, Qinghai, Peoples R China.
发表日期	2021
ISSN	0147-6513
EISSN	1090-2414
卷号	228
英文摘要	The construction of hydropower projects discharges effluents to aquatic bodies. The effluents consist of different chemicals including heavy metals. The current study assessed the effects of effluents discharged from an underconstruction hydropower project on the bioaccumulation of heavy metals in the tissues of critically endangered Tor putitora (Hamilton, 1822) in the river Panjkora. The subsequent toxic impacts of higher bioaccumulation of heavy metals on different biochemical, hematological, and serum biochemical profiles were also studied. Different biochemical changes were observed in the tissues of T. putitora including stress biomarkers such as reactive oxygen species, lipid peroxidation, total protein contents, antioxidant enzymes (peroxidase, superoxide dismutase, catalase, reduced glutathione, glutathione reductase, and glutathione-s-transferase), acetylcholinesterase, and whole-body cortisol. The hematotoxic effects were also observed as the count of red blood cells, hematocrit, and hemoglobin decreased whereas the count of white blood cells increased. Serum biochemical analysis revealed that cholesterol, urea, total bilirubin, and glucose concentration increased, whereas total proteins and albumin decreased with an increase in the concentration of heavy metals across the sampling sites. The fish from the river was found to be under severe stress as compared to the fish from the reference site. To mitigate the current scenario, stocking fish in an appropriate amount is suggested. The fish diversity and water quality should be assessed at regular intervals to avoid further deterioration and diversity loss. The safety and conservation of wild fisheries should be ensured by implementing strict environmental protection and fishing laws.
关键词	FRESH-WATER FISH INDUCED OXIDATIVE STRESS RIVER PANJKORA KHYBER PAKHTUNKHWA CHANNA-PUNCTATUS LOWER DIR GLUTATHIONE ZN CU ANTIOXIDANT
英文关键词	Hydropower projects; Effluents; Biochemical disruption; Cortisol assay; Hematotoxicity; Serum biochemistry
语种	英语
WOS研究方向	Environmental Sciences & Ecology ; Toxicology
WOS类目	Environmental Sciences ; Toxicology
WOS记录号	WOS:000740121400001
来源期刊	ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
来源机构	中国科学院西北生态环境资源研究院
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/254749
作者单位	[Ullah, Sana; Li, Zhongqiu] Nanjing Univ, Sch Life Sci, Anim Behav & Conservat Lab, Nanjing 210023, Jiangsu, Peoples R China; [Ullah, Sana] Univ Educ, Div Sci & Technol, Dept Zool, Lahore 54000, Pakistan; [Hassan, Said] Bacha Khan Univ, Dept Biotechnol, Charsadda 24461, Khyber Pakhtunk, Pakistan; [Ahmad, Shahid; Nabi, Ghulam] Hebei Normal Univ, Coll Life Sci, Key Lab Anim Physiol Biochem & Mol Biol Hebei Pro, Shijiazhuang 050010, Hebei, Peoples R China; [Guo, Xinle] Qinghai Normal Univ, Acad Plateau Sci & Sustainabil, Coll Life Sci, Xining, Peoples R China; [Wanghe, Kunyuan] Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, Qinghai Prov Key Lab Anim Ecol Genom, 23th Xinning Rd, Xining 810008, Qinghai, Peoples R China
推荐引用方式 GB/T 7714	Ullah, Sana,Li, Zhongqiu,Hassan, Said,et al. Heavy metals bioaccumulation and subsequent multiple biomarkers based appraisal of toxicity in the critically endangered Tor putitora[J]. 中国科学院西北生态环境资源研究院,2021,228.
APA	Ullah, Sana.,Li, Zhongqiu.,Hassan, Said.,Ahmad, Shahid.,Guo, Xinle.,...&Nabi, Ghulam.(2021).Heavy metals bioaccumulation and subsequent multiple biomarkers based appraisal of toxicity in the critically endangered Tor putitora.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,228.
MLA	Ullah, Sana,et al."Heavy metals bioaccumulation and subsequent multiple biomarkers based appraisal of toxicity in the critically endangered Tor putitora".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 228(2021).