气候变化领域集成服务门户(CCPortal): Cave Microbes as a Potential Source of Drugs Development in the Modern Era

CCPortal

DOI	10.1007/s00248-021-01889-3
	Cave Microbes as a Potential Source of Drugs Development in the Modern Era
	Zada, Sahib; Sajjad, Wasim; Rafiq, Muhammad; Ali, Sardar; Hu, Zhong; Wang, Hui; Cai, Runlin
通讯作者	Cai, RL (通讯作者)，Shantou Univ, Coll Sci, Inst Marine Sci, Biol Dept,Guangdong Prov Key Lab Marine Biotechno, Shantou, Peoples R China.
发表日期	2020
ISSN	0095-3628
EISSN	1432-184X
英文摘要	The world is constantly facing threats, including the emergence of new pathogens and antibiotic resistance among extant pathogens, which is a matter of concern. Therefore, the need for natural and effective sources of drugs is inevitable. The ancient and pristine ecosystems of caves contain a unique microbial world and could provide a possible source of antimicrobial metabolites. The association between humans and caves is as old as human history itself. Historically, cave environments have been used to treat patients with respiratory tract infections, which is referred to as speleotherapy. Today, the pristine environment of caves that comprise a poorly explored microbial world is a potential source of antimicrobial and anticancer drugs. Oligotrophic conditions in caves enhance the competition among microbial communities, and unique antimicrobial agents may be used in this competition. This review suggests that the world needs a novel and effective source of drug discovery. Therefore, being the emerging spot of modern human civilization, caves could play a crucial role in the current medical crisis, and cave microorganisms may have the potential to produce novel antimicrobial and anticancer drugs.
关键词	GLOBAL HEALTH SECURITY ZIKA VIRUS BATS DNA
英文关键词	Cave ecosystem; Antibiotic resistance; Antimicrobial drugs; Speleotherapy
语种	英语
WOS研究方向	Environmental Sciences & Ecology ; Marine & Freshwater Biology ; Microbiology
WOS类目	Ecology ; Marine & Freshwater Biology ; Microbiology
WOS记录号	WOS:000710343500001
来源期刊	MICROBIAL ECOLOGY
来源机构	中国科学院西北生态环境资源研究院
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/254715
作者单位	[Zada, Sahib; Ali, Sardar; Hu, Zhong; Wang, Hui; Cai, Runlin] Shantou Univ, Coll Sci, Inst Marine Sci, Biol Dept,Guangdong Prov Key Lab Marine Biotechno, Shantou, Peoples R China; [Sajjad, Wasim] Chinese Acad Sci, Northwest Inst Ecoenvironm & Resources, State Key Lab Cryospher Sci, Lanzhou 730000, Peoples R China; [Rafiq, Muhammad] Balochistan Univ IT Engn & Management Sci, Fac Life Sci & Informat, Dept Microbiol, Quetta, Pakistan
推荐引用方式 GB/T 7714	Zada, Sahib,Sajjad, Wasim,Rafiq, Muhammad,et al. Cave Microbes as a Potential Source of Drugs Development in the Modern Era[J]. 中国科学院西北生态环境资源研究院,2020.
APA	Zada, Sahib.,Sajjad, Wasim.,Rafiq, Muhammad.,Ali, Sardar.,Hu, Zhong.,...&Cai, Runlin.(2020).Cave Microbes as a Potential Source of Drugs Development in the Modern Era.MICROBIAL ECOLOGY.
MLA	Zada, Sahib,et al."Cave Microbes as a Potential Source of Drugs Development in the Modern Era".MICROBIAL ECOLOGY (2020).