气候变化领域集成服务门户(CCPortal): Diterpenoid Alkaloids from the Aerial Parts of Aconitum flavum Hand.-Mazz

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DOI	10.1007/s13659-021-00302-3
	Diterpenoid Alkaloids from the Aerial Parts of Aconitum flavum Hand.-Mazz
	Zhang, Na; Xia, Fan; Li, Song-Yu; Nian, Yin; Wei, Li-Xin; Xu, Gang
通讯作者	Xu, G (通讯作者)，Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China. ; Xu, G (通讯作者)，Chinese Acad Sci, Kunming Inst Bot, Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China.
发表日期	2021
ISSN	2192-2195
EISSN	2192-2209
起始页码	421
结束页码	429
卷号	11 期号:4
英文摘要	Sixteen diterpenoid alkaloids (DAs), including six aconitine-type alkaloids (5 and 9 - 13), seven 7,17-seco-aconitine-type alkaloids (1 - 4, 6 - 8), two napelline-type alkaloids (14 and 15) as well as one veatchine-type alkaloid (16), were isolated from the aerial parts of Aconitum flavum Hand.-Mazz. In which, flavumolines A - D (1 - 4) were four new ones, and flavumoline E (5) was reported as natural compound for the first time. Their chemical structures were elucidated by the analysis of extensive spectroscopic data. The inhibitory activities of these isolates on Ca(v)3.1 low voltage-gated Ca2+ channel, NO production in LPS-activated RAW264.7cells, five human tumor cell lines, as well as acetylcholinesterase (AChE) were tested.
英文关键词	Aconitum flavum Hand; -Mazz; Diterpenoid alkaloids; Bioactivity
语种	英语
WOS研究方向	Pharmacology & Pharmacy
WOS类目	Chemistry, Medicinal
WOS记录号	WOS:000640741900001
来源期刊	NATURAL PRODUCTS AND BIOPROSPECTING
来源机构	中国科学院西北生态环境资源研究院
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/254567
作者单位	[Zhang, Na; Xia, Fan; Li, Song-Yu; Nian, Yin; Xu, Gang] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China; [Zhang, Na; Xia, Fan; Li, Song-Yu; Nian, Yin; Xu, Gang] Chinese Acad Sci, Kunming Inst Bot, Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China; [Zhang, Na; Li, Song-Yu] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Wei, Li-Xin] Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining, Qinghai, Peoples R China; [Wei, Li-Xin] Chinese Acad Sci, Northwest Inst Plateau Biol, Qinghai Prov Key Lab Tibetan Med Pharmacol & Safe, Xining, Qinghai, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Na,Xia, Fan,Li, Song-Yu,et al. Diterpenoid Alkaloids from the Aerial Parts of Aconitum flavum Hand.-Mazz[J]. 中国科学院西北生态环境资源研究院,2021,11(4).
APA	Zhang, Na,Xia, Fan,Li, Song-Yu,Nian, Yin,Wei, Li-Xin,&Xu, Gang.(2021).Diterpenoid Alkaloids from the Aerial Parts of Aconitum flavum Hand.-Mazz.NATURAL PRODUCTS AND BIOPROSPECTING,11(4).
MLA	Zhang, Na,et al."Diterpenoid Alkaloids from the Aerial Parts of Aconitum flavum Hand.-Mazz".NATURAL PRODUCTS AND BIOPROSPECTING 11.4(2021).