气候变化领域集成服务门户(CCPortal): Dual-signal based immunoassay for colorimetric and photothermal detection of furazolidone

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DOI	10.1016/j.snb.2020.129431
	Dual-signal based immunoassay for colorimetric and photothermal detection of furazolidone
	Su, Lihong; Chen, Yaqian; Wang, Lulu; Zhang, Han; Sun, Jing; Wang, Jianlong; Zhang, Daohong
通讯作者	Zhang, DH (通讯作者)，Northwest A&F Univ, Coll Food Sci & Engn, Yangling 712100, Shaanxi, Peoples R China.
发表日期	2021
EISSN	0925-4005
卷号	331
英文摘要	As a point-of-care testing method, lateral flow immunoassays are attracting extensive attentions for antibiotic residue detections; however, immunoassay techniques for qualitative and quantitative detections are limited by the poor sensitivity and requirement for cumbersome quantitative devices. To overcome these limitations, MnO2-Au, with an excellent carrying capacity of Au nanoparticles and high photothermal signals, was introduced and a dual-signal immunoassay using colorimetric/photothermal MnO2-Au signal probe was proposed for furazolidone (FZD) detection. The dual-signal immunoassay not only enables visual detection relying on color change, but also enables quantitative detection via converting conventional assay signals into heat signals using a thermal infrared imager recording. Based on the excellent light-to-heat conversion activity of the bifunctional MnO2-Au, the FZD metabolite of 3-amino-2-oxazolidinone (AOZ) can be qualitatively detected in virtue of colorimetric signals with a visual limit of 1 ng mL(-1) and quantitatively detected by photothermal signals with a detection limit of 0.43 ng mL(-1). The dual-signal immunoassay biosensor was well applied in food samples with acceptable recoveries of 80.6-106 %. The immunoassay that integrates colorimetric and photothermal analysis will hold a broader application area in real-time monitoring.
英文关键词	Furazolidone; Immunoassay; Dual-signal; Food safety
语种	英语
WOS研究方向	Chemistry ; Electrochemistry ; Instruments & Instrumentation
WOS类目	Chemistry, Analytical ; Electrochemistry ; Instruments & Instrumentation
WOS记录号	WOS:000618767800002
来源期刊	SENSORS AND ACTUATORS B-CHEMICAL
来源机构	中国科学院西北生态环境资源研究院
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/254464
作者单位	[Su, Lihong; Chen, Yaqian; Wang, Lulu; Zhang, Han; Wang, Jianlong; Zhang, Daohong] Northwest A&F Univ, Coll Food Sci & Engn, Yangling 712100, Shaanxi, Peoples R China; [Sun, Jing] Chinese Acad Sci, Northwest Inst Plateau Biol, Qinghai Key Lab Qinghai Tibet Plateau Biol Resour, Xining 810008, Qinghai, Peoples R China
推荐引用方式 GB/T 7714	Su, Lihong,Chen, Yaqian,Wang, Lulu,et al. Dual-signal based immunoassay for colorimetric and photothermal detection of furazolidone[J]. 中国科学院西北生态环境资源研究院,2021,331.
APA	Su, Lihong.,Chen, Yaqian.,Wang, Lulu.,Zhang, Han.,Sun, Jing.,...&Zhang, Daohong.(2021).Dual-signal based immunoassay for colorimetric and photothermal detection of furazolidone.SENSORS AND ACTUATORS B-CHEMICAL,331.
MLA	Su, Lihong,et al."Dual-signal based immunoassay for colorimetric and photothermal detection of furazolidone".SENSORS AND ACTUATORS B-CHEMICAL 331(2021).