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DOI	10.1016/j.foodchem.2021.130737
	Controllable assembly metal-organic frameworks and gold nanoparticles composites for sensitive immunochromatographic assay
	Yin, Xuechi; Dou, Leina; Yao, Xiaolin; Liu, Sijie; Zhang, Liang; Zhao, Man; Su, Lihong; Sun, Jing; Wang, Jianlong; Zhang, Daohong
通讯作者	Zhang, DH (通讯作者)，Northwest A&F Univ, Coll Food Sci & Engn, Yangling 712100, Shaanxi, Peoples R China.
发表日期	2022
ISSN	0308-8146
EISSN	1873-7072
卷号	367
英文摘要	Creating universal signal labels from fundamental building blocks with excellent biocompatibility and wellcontrolled size/uniformity simultaneously for immunochromatographic assay (ICA) is highly desired but extremely challenging. Here, a nano-signal label strategy was reported, in which the amino-terminated zirconium MOFs (NU66) are adopted to construct powerful matrix materials and gold nanoparticles (AuNPs) act as the linker between metal-organic frameworks (MOFs) and antibodies. Particularly, AuNPs were immobilized directly on the surface of NU66, giving NU66 excellent biocompatibility with bright color signal labels and improving the salt ion stability of AuNPs. As a proof of concept, the furazolidone residues was monitored by the developed NU66@AuNPs-ICA in food samples (pork, shrimp and eggs). With 3-[(4-carboxyphenyl) monomethyl] amino-2oxazolidinone (CPAOZ) as analyte target, the visual limit of detection (vLOD) and cut-off level were 0.6 ng/mL and 3.0 ng/mL, respectively. This work may open a new avenue for the application of MOFs in immunochromatography assays.
关键词	FLOW ELECTROCHEMILUMINESCENCE PERFORMANCE PLATFORM STRIP
英文关键词	Immunochromatographic assay; Metal-organic frameworks; AuNPs; Label strategy; Furazolidone
语种	英语
WOS研究方向	Chemistry ; Food Science & Technology ; Nutrition & Dietetics
WOS类目	Chemistry, Applied ; Food Science & Technology ; Nutrition & Dietetics
WOS记录号	WOS:000697252200007
来源期刊	FOOD CHEMISTRY
来源机构	中国科学院西北生态环境资源研究院
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/254112
作者单位	[Yin, Xuechi; Dou, Leina; Yao, Xiaolin; Liu, Sijie; Zhang, Liang; Zhao, Man; Su, Lihong; Wang, Jianlong; Zhang, Daohong] Northwest A&F Univ, Coll Food Sci & Engn, Yangling 712100, Shaanxi, Peoples R China; [Sun, Jing] Chinese Acad Sci, Northwest Inst Plateau Biol, Qinghai Key Lab Qinghai Tibet Plateau Biol Resour, Xining 810008, Qinghai, Peoples R China
推荐引用方式 GB/T 7714	Yin, Xuechi,Dou, Leina,Yao, Xiaolin,et al. Controllable assembly metal-organic frameworks and gold nanoparticles composites for sensitive immunochromatographic assay[J]. 中国科学院西北生态环境资源研究院,2022,367.
APA	Yin, Xuechi.,Dou, Leina.,Yao, Xiaolin.,Liu, Sijie.,Zhang, Liang.,...&Zhang, Daohong.(2022).Controllable assembly metal-organic frameworks and gold nanoparticles composites for sensitive immunochromatographic assay.FOOD CHEMISTRY,367.
MLA	Yin, Xuechi,et al."Controllable assembly metal-organic frameworks and gold nanoparticles composites for sensitive immunochromatographic assay".FOOD CHEMISTRY 367(2022).