气候变化领域集成服务门户(CCPortal): Ce4+-triggered cascade reaction for ratiometric fluorescence detection of alendronate

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DOI	10.1016/j.saa.2021.119437
	Ce4+-triggered cascade reaction for ratiometric fluorescence detection of alendronate
	Xia, Meng; Shi, Fengjin; Xia, Yinghui; Sun, Jing; Zhao, Xian-En; Zhu, Shuyun
通讯作者	Zhao, XE ; Zhu, SY (通讯作者)，Qufu Normal Univ, Sch Chem & Chem Engn, Qufu 273165, Shandong, Peoples R China.
发表日期	2021
ISSN	1386-1425
EISSN	1873-3557
卷号	251
英文摘要	A ratiometric fluorescence assay for alendronate (ALDS) has been designed with Ce4+-triggered cascade chromogenic reaction. This strategy involves three processes: (1) Ce4+ oxidizes ascorbic acid (AA) into dehydroascorbic acid (DHAA), which then condenses with o-phenlenediamine (OPD) to generate fluorescent 3(dihydroxyethyl)furo[3,4-b] quinoxaline-1-one (DFQ), presenting the maximum emission at 434 nm; (2) As oxidase-mimics, Ce4+ can oxidize OPD into fluorescent 2,3-diaminophenazine (DAP) which shows a strong emission at 568 nm; (3) ALDS inhibits the oxidation ability of Ce4+ towards OPD, thus inhibiting the generation of DAP. Accordingly, a homogeneous ratiometric fluorescence system with dual emission comes into being and the presence of ALDS can change the fluorescence intensity ratio obviously. With F434/F568 as readout, ALDS can be detected sensitively with the detection limit of 30 nM. Moreover, this ratiometric method was used to analyze ALDS in both human serum and pharmaceutical samples. (c) 2021 Elsevier B.V. All rights reserved.
关键词	SPECTROPHOTOMETRIC DETERMINATION CARBON DOTS HIGH-SENSITIVITY ASCORBIC-ACID SODIUM SENSOR OXIDATION NANOSENSOR GREEN METAL
英文关键词	Ratiometric fluorescence sensor; Cascade reaction; Oxidase-mimics; Ce4+; O-Phenlenediamine; Ascorbic acid
语种	英语
WOS研究方向	Spectroscopy
WOS类目	Spectroscopy
WOS记录号	WOS:000621417000007
来源期刊	SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
来源机构	中国科学院西北生态环境资源研究院
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/254099
作者单位	[Xia, Meng; Shi, Fengjin; Xia, Yinghui; Zhao, Xian-En; Zhu, Shuyun] Qufu Normal Univ, Sch Chem & Chem Engn, Qufu 273165, Shandong, Peoples R China; [Sun, Jing] Chinese Acad Sci, Qinghai Key Lab Qinghai Tibet Plateau Biol Resour, Northwest Inst Plateau Biol, Xining 810001, Peoples R China
推荐引用方式 GB/T 7714	Xia, Meng,Shi, Fengjin,Xia, Yinghui,et al. Ce4+-triggered cascade reaction for ratiometric fluorescence detection of alendronate[J]. 中国科学院西北生态环境资源研究院,2021,251.
APA	Xia, Meng,Shi, Fengjin,Xia, Yinghui,Sun, Jing,Zhao, Xian-En,&Zhu, Shuyun.(2021).Ce4+-triggered cascade reaction for ratiometric fluorescence detection of alendronate.SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,251.
MLA	Xia, Meng,et al."Ce4+-triggered cascade reaction for ratiometric fluorescence detection of alendronate".SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 251(2021).