气候变化领域集成服务门户(CCPortal): Three new dihydroflavonols with free radical scavenging activity from Ribes himalense Royle ex Decne

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DOI	10.1080/14786419.2021.2017929
	Three new dihydroflavonols with free radical scavenging activity from Ribes himalense Royle ex Decne
	Liu, Chuang; Lei, Yuqing; Li, Gang; Yuan, Chen; Lv, Yue; Yu, Song; Shao, Yun; Dang, Jun
通讯作者	Shao, Y ; Dang, J (通讯作者)，Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining, Qinghai, Peoples R China.
发表日期	2020
ISSN	1478-6419
EISSN	1478-6427
英文摘要	Ribes himalense Royle ex Decne, a small shrub, is widely used as a Tibetan medicine in Chinese folk. In this study, three novel 1,1-diphenyl-2-picrylhydrazyl inhibitors named Rihimaside A, Rihimaside B, and Rihimaside C, as well as one known 1,1-diphenyl-2-picrylhydrazyl inhibitor, dihydromyricetin, were isolated from the leaves and stems of Ribes himalense Royle ex Decne using online high performance liquid chromatography-1,1-diphenyl-2-picrylhydrazyl activity screening system combined with medium and high-pressure liquid chromatography. All four 1,1-diphenyl-2-picrylhydrazyl inhibitors are dihydroflavonols. The 1,1-diphenyl-2-picrylhydrazyl scavenging activity and IC50 values of three novel 1,1-diphenyl-2-picrylhydrazyl inhibitors were determined using 1,1-diphenyl-2-picrylhydrazyl methods. Rihimaside A, Rihimaside B, and Rihimaside C exhibited IC50 values of 9.58 mu g/mL, 12.57 mu g/mL and 387 mu g/mL, respectively.
关键词	ANTIOXIDANT
英文关键词	Ribes himalense; dihydroflavonols; liquid chromatography; structure identification; 1; 1-diphenyl-2-picrylhydrazyl scavenging activity
语种	英语
WOS研究方向	Chemistry ; Pharmacology & Pharmacy
WOS类目	Chemistry, Applied ; Chemistry, Medicinal
WOS记录号	WOS:000733789300001
来源期刊	NATURAL PRODUCT RESEARCH
来源机构	中国科学院西北生态环境资源研究院
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/254054
作者单位	[Liu, Chuang; Shao, Yun; Dang, Jun] Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining, Qinghai, Peoples R China; [Liu, Chuang; Lei, Yuqing] Univ Chinese Acad Sci, Beijing, Peoples R China; [Li, Gang; Yuan, Chen; Lv, Yue] Yantai Univ, Coll Life Sci, Ctr Mitochondria & Hlth Aging, Yantai, Peoples R China; [Yu, Song] Qinghai Univ, Dept Med Coll, Xining, Peoples R China
推荐引用方式 GB/T 7714	Liu, Chuang,Lei, Yuqing,Li, Gang,et al. Three new dihydroflavonols with free radical scavenging activity from Ribes himalense Royle ex Decne[J]. 中国科学院西北生态环境资源研究院,2020.
APA	Liu, Chuang.,Lei, Yuqing.,Li, Gang.,Yuan, Chen.,Lv, Yue.,...&Dang, Jun.(2020).Three new dihydroflavonols with free radical scavenging activity from Ribes himalense Royle ex Decne.NATURAL PRODUCT RESEARCH.
MLA	Liu, Chuang,et al."Three new dihydroflavonols with free radical scavenging activity from Ribes himalense Royle ex Decne".NATURAL PRODUCT RESEARCH (2020).