气候变化领域集成服务门户(CCPortal): Differences in Gut Microbiome Composition and Antibiotic Resistance Gene Distribution between Chinese and Pakistani University Students from a Common Peer Group

CCPortal

DOI	10.3390/microorganisms9061152
	Differences in Gut Microbiome Composition and Antibiotic Resistance Gene Distribution between Chinese and Pakistani University Students from a Common Peer Group
	Feng, Tianshu; Hilal, Mian Gul; Wang, Yijie; Zhou, Rui; Yu, Qiaoling; Qu, Jiapeng; Li, Huan
通讯作者	Li, H (通讯作者)，Lanzhou Univ, Sch Publ Hlth, Lanzhou 730000, Peoples R China. ; Qu, JP (通讯作者)，Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, Xining 810008, Peoples R China. ; Li, H (通讯作者)，Lanzhou Univ, Ctr Grassland Microbiome, Lanzhou 730000, Peoples R China.
发表日期	2021
EISSN	2076-2607
卷号	9 期号:6
英文摘要	Gut microbiomes play important functional roles in human health and are also affected by many factors. However, few studies concentrate on gut microbiomes under exercise intervention. Additionally, antibiotic resistance genes (ARGs) carried by gut microbiomes may constantly pose a threat to human health. Here, ARGs and microbiomes of Chinese and Pakistanis participants were investigated using 16S rRNA gene sequencing and high-throughput quantitative PCR techniques. The exercise had no impact on gut microbiomes in the 12 individuals investigated during the observation period, while the different distribution of gut microbiomes was found in distinct nationalities. Overall, the dominant microbial phyla in the participants' gut were Bacteroidota, Firmicutes and Proteobacteria. Some genera such as Prevotella and Dialister were more abundant in Pakistani participants and some other genera such as Bacteroides and Faecalibacterium were more abundant in Chinese participants. The microbial diversity in Chinese was higher than that in Pakistanis. Furthermore, microbial community structures were also different between Chinese and Pakistanis. For ARGs, the distribution of all detected ARGs is not distinct at each time point. Among these ARGs, floR was distributed differently in Chinese and Pakistani participants, and some ARGs such as tetQ and sul2 are positively correlated with several dominant microbiomes, particularly Bacteroidota and Firmicutes bacteria that did not fluctuate over time.
关键词	DIETARY FIBER DIVERSITY POPULATIONS GENOME METABOLISM STABILITY PATTERNS METAXA2 MANURE AGE
英文关键词	gut microbiota; nationalities; stabilization; antibiotic resistance genes (ARGs); human health
语种	英语
WOS研究方向	Microbiology
WOS类目	Microbiology
WOS记录号	WOS:000666323600001
来源期刊	MICROORGANISMS
来源机构	中国科学院西北生态环境资源研究院
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/253894
作者单位	[Feng, Tianshu; Hilal, Mian Gul; Wang, Yijie; Zhou, Rui; Yu, Qiaoling; Li, Huan] Lanzhou Univ, Sch Publ Hlth, Lanzhou 730000, Peoples R China; [Qu, Jiapeng] Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, Xining 810008, Peoples R China; [Li, Huan] Lanzhou Univ, Ctr Grassland Microbiome, Lanzhou 730000, Peoples R China
推荐引用方式 GB/T 7714	Feng, Tianshu,Hilal, Mian Gul,Wang, Yijie,et al. Differences in Gut Microbiome Composition and Antibiotic Resistance Gene Distribution between Chinese and Pakistani University Students from a Common Peer Group[J]. 中国科学院西北生态环境资源研究院,2021,9(6).
APA	Feng, Tianshu.,Hilal, Mian Gul.,Wang, Yijie.,Zhou, Rui.,Yu, Qiaoling.,...&Li, Huan.(2021).Differences in Gut Microbiome Composition and Antibiotic Resistance Gene Distribution between Chinese and Pakistani University Students from a Common Peer Group.MICROORGANISMS,9(6).
MLA	Feng, Tianshu,et al."Differences in Gut Microbiome Composition and Antibiotic Resistance Gene Distribution between Chinese and Pakistani University Students from a Common Peer Group".MICROORGANISMS 9.6(2021).