气候变化领域集成服务门户(CCPortal): Characterization of the bacterial microbiota across the different intestinal segments of the Qinghai semi-fine wool sheep on the Qinghai-Tibetan Plateau

CCPortal

DOI	10.5713/ab.20.0809
	Characterization of the bacterial microbiota across the different intestinal segments of the Qinghai semi-fine wool sheep on the Qinghai-Tibetan Plateau
	Wang, Xungang; Hu, Linyong; Liu, Hongjin; Xu, Tianwei; Zhao, Na; Zhang, Xiaoling; Geng, Yuanyue; Kang, Shengping; Xu, Shixiao
通讯作者	Xu, SX (通讯作者)，Chinese Acad Sci, Northwest Inst Plateau Biol, Xining 810001, Peoples R China.
发表日期	2021
ISSN	2765-0189
EISSN	2765-0235
起始页码	1921
结束页码	1929
卷号	34 期号:12
英文摘要	Objective: The intestinal microbiota enhances nutrient absorption in the host and thus promotes heath. Qinghai semi-fine wool sheep is an important livestock raised in the Qinghai Tibetan Plateau; however, little is known about the bacterial microbiota of its intestinal tract. The aim of this study was to detect the microbial characterization in the intestinal tract of the Qinghai semi-fine wool sheep. Methods: The bacterial profiles of the six different intestinal segments (duodenum, jejunum, ileum, cecum, colon and rectum) of Qinghai semi-fine wool sheep were studied using 16S rRNA V3-V4 hypervariable amplicon sequencing. Results: A total of 2,623,323 effective sequences were obtained, and 441 OTUs shared all six intestinal segments. The bacterial diversity was significantly different among the different intestinal segments, and the large intestine exhibited higher bacterial diversity than the small intestine. Firmicutes, Bacteroidetes, and Patescibacteria were the dominant phyla in these bacterial communities. Additionally, at the genus level, Prevotella_1, Candidatus_ Saccharimonas, and Ruminococcaceae_UCG-005 were the most predominant genus in duodenal segment, jejunal and ileal segments, and cecal, colonic, and rectal segments, respectively. We predicted that the microbial functions and the relative abundance of the genes involved in carbohydrate metabolism were overrepresented in the intestinal segments of Qinghai semi-fine wool sheep. Conclusion: The bacterial communities and functions differed among different intestinal segments. Our study is the first to provide insights into the composition and biological functions of the intestinal microbiota of Qinghai semi-fine wool sheep. Our results also provide useful information for the nutritional regulation and production development in Qinghai semi-fine wool sheep.
关键词	GASTROINTESTINAL-TRACT
英文关键词	High-throughput Sequencing; Intestine; Microbiota; Qinghai Semi-fine Wool Sheep; Qinghai-Tibetan Plateau
语种	英语
WOS研究方向	Agriculture
WOS类目	Agriculture, Dairy & Animal Science
WOS记录号	WOS:000710235800006
来源期刊	ANIMAL BIOSCIENCE
来源机构	中国科学院西北生态环境资源研究院
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/253724
作者单位	[Wang, Xungang; Hu, Linyong; Liu, Hongjin; Xu, Tianwei; Zhao, Na; Zhang, Xiaoling; Geng, Yuanyue; Kang, Shengping; Xu, Shixiao] Chinese Acad Sci, Northwest Inst Plateau Biol, Xining 810001, Peoples R China; [Zhang, Xiaoling; Geng, Yuanyue; Kang, Shengping] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Wang, Xungang,Hu, Linyong,Liu, Hongjin,et al. Characterization of the bacterial microbiota across the different intestinal segments of the Qinghai semi-fine wool sheep on the Qinghai-Tibetan Plateau[J]. 中国科学院西北生态环境资源研究院,2021,34(12).
APA	Wang, Xungang.,Hu, Linyong.,Liu, Hongjin.,Xu, Tianwei.,Zhao, Na.,...&Xu, Shixiao.(2021).Characterization of the bacterial microbiota across the different intestinal segments of the Qinghai semi-fine wool sheep on the Qinghai-Tibetan Plateau.ANIMAL BIOSCIENCE,34(12).
MLA	Wang, Xungang,et al."Characterization of the bacterial microbiota across the different intestinal segments of the Qinghai semi-fine wool sheep on the Qinghai-Tibetan Plateau".ANIMAL BIOSCIENCE 34.12(2021).