气候变化领域集成服务门户(CCPortal): Alkaloids and phenolics identification in fruit of Nitraria tangutorum Bobr. by UPLC-Q-TOF-MS/MS and their a-glucosidase inhibitory effects in vivo and in vitro

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DOI	10.1016/j.foodchem.2021.130412
	Alkaloids and phenolics identification in fruit of Nitraria tangutorum Bobr. by UPLC-Q-TOF-MS/MS and their a-glucosidase inhibitory effects in vivo and in vitro
	Jiang, Sirong; Chen, Chen; Dong, Qi; Shao, Yun; Zhao, Xiaohui; Tao, Yanduo; Yue, Huilan
通讯作者	Zhao, XH ; Yue, HL (通讯作者)，Northwest Inst Plateau Biol, Qinghai Prov Key Lab Tibetan Med Res, Xining 810008, Qinghai, Peoples R China. ; Zhao, XH ; Yue, HL (通讯作者)，Northwest Inst Plateau Biol, CAS Key Lab Tibetan Med Res, Xining 810008, Qinghai, Peoples R China.
发表日期	2021
ISSN	0308-8146
EISSN	1873-7072
卷号	364
英文摘要	Nitraria tangutorum Bobr. (NTB), mainly distributed in the Qaidam Basin of Tibetan Plateau, have high economic, ecological and medicinal value. The chemical compositions in the NTB fruits were tentatively analyzed and characterized by applying UPLC-Q-TOF-MS/MS. Total 45 constituents, including 9 hydroxycinnamic acids derivatives, 12 flavonols, 4 flavonoids, 1 trolox derivative, 8 beta-carboline alkaloids, 4 tryptophan derivatives, and 7 other amino acid derivatives were identified by comparing with standard products, and analyzing their retention times, characteristic fragment ions and deprotonated molecule ions. The activity studies in vitro indicated that NTB-Z and NTB-C extracts had marked inhibitory effects against sucrase and maltase. Further sucrose/maltose/starch tolerance experiment demonstrated that both NTB-Z and NTB-C extracts at 400 mg/kg could markedly lower the postprandial blood glucose (PBG) level in diabetic animals. All these results indicated that the NTB fruits could be used as the functional health food or medicine for controlling postprandial blood glucose level.
关键词	ALPHA-GLUCOSIDASE POSTPRANDIAL HYPERGLYCEMIA ANTIOXIDANT FLAVONOIDS ANTHOCYANINS
英文关键词	Nitraria tangutorum Bobr; flavonoids; Phenolic acids; Alkaloids; Postprandial blood glucose; Sucrose; Maltase
语种	英语
WOS研究方向	Chemistry ; Food Science & Technology ; Nutrition & Dietetics
WOS类目	Chemistry, Applied ; Food Science & Technology ; Nutrition & Dietetics
WOS记录号	WOS:000685896900011
来源期刊	FOOD CHEMISTRY
来源机构	中国科学院西北生态环境资源研究院
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/253603
作者单位	[Jiang, Sirong; Chen, Chen; Dong, Qi; Shao, Yun; Zhao, Xiaohui; Tao, Yanduo; Yue, Huilan] Northwest Inst Plateau Biol, Qinghai Prov Key Lab Tibetan Med Res, Xining 810008, Qinghai, Peoples R China; [Jiang, Sirong; Chen, Chen; Dong, Qi; Shao, Yun; Zhao, Xiaohui; Tao, Yanduo; Yue, Huilan] Northwest Inst Plateau Biol, CAS Key Lab Tibetan Med Res, Xining 810008, Qinghai, Peoples R China; [Jiang, Sirong] Univ Chinese Acad Sci, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Jiang, Sirong,Chen, Chen,Dong, Qi,et al. Alkaloids and phenolics identification in fruit of Nitraria tangutorum Bobr. by UPLC-Q-TOF-MS/MS and their a-glucosidase inhibitory effects in vivo and in vitro[J]. 中国科学院西北生态环境资源研究院,2021,364.
APA	Jiang, Sirong.,Chen, Chen.,Dong, Qi.,Shao, Yun.,Zhao, Xiaohui.,...&Yue, Huilan.(2021).Alkaloids and phenolics identification in fruit of Nitraria tangutorum Bobr. by UPLC-Q-TOF-MS/MS and their a-glucosidase inhibitory effects in vivo and in vitro.FOOD CHEMISTRY,364.
MLA	Jiang, Sirong,et al."Alkaloids and phenolics identification in fruit of Nitraria tangutorum Bobr. by UPLC-Q-TOF-MS/MS and their a-glucosidase inhibitory effects in vivo and in vitro".FOOD CHEMISTRY 364(2021).