气候变化领域集成服务门户(CCPortal): GABA signalling modulates stomatal opening to enhance plant water use efficiency and drought resilience

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DOI	10.1038/s41467-021-21694-3
	GABA signalling modulates stomatal opening to enhance plant water use efficiency and drought resilience
	Xu B.; Long Y.; Feng X.; Zhu X.; Sai N.; Chirkova L.; Betts A.; Herrmann J.; Edwards E.J.; Okamoto M.; Hedrich R.; Gilliham M.
发表日期	2021
ISSN	2041-1723
卷号	12 期号:1
英文摘要	The non-protein amino acid γ-aminobutyric acid (GABA) has been proposed to be an ancient messenger for cellular communication conserved across biological kingdoms. GABA has well-defined signalling roles in animals; however, whilst GABA accumulates in plants under stress it has not been determined if, how, where and when GABA acts as an endogenous plant signalling molecule. Here, we establish endogenous GABA as a bona fide plant signal, acting via a mechanism not found in animals. Using Arabidopsis thaliana, we show guard cell GABA production is necessary and sufficient to reduce stomatal opening and transpirational water loss, which improves water use efficiency and drought tolerance, via negative regulation of a stomatal guard cell tonoplast-localised anion transporter. We find GABA modulation of stomata occurs in multiple plants, including dicot and monocot crops. This study highlights a role for GABA metabolism in fine tuning physiology and opens alternative avenues for improving plant stress resilience. © 2021, The Author(s).
语种	英语
scopus关键词	4 aminobutyric acid; 4 aminobutyric acid A receptor; 4 aminobutyric acid receptor; abscisic acid; amino acid; anion; aromatic amino acid; calcium calmodulin dependent protein kinase; coronatine; cysteine loop ligand gated ion channel receptor; DNA; DNA polymerase; glutamate decarboxylase; muscimol; 4 aminobutyric acid; abscisic acid; ALMT9 protein, Arabidopsis; Arabidopsis protein; chloride channel; fusion protein; glutamate decarboxylase; glutamate decarboxylase 2; green fluorescent protein; isoenzyme; water; amino acid; cell component; chemical compound; detection method; drought; metabolism; stomata; water use efficiency; 4 aminobutyric acid metabolism; Arabidopsis thaliana; Article; climate resilience; crop; drought; drought resilience; drought stress; drought tolerance; guard cell; monocot; nonhuman; physiological process; plant water use; regulatory mechanism; signal transduction; stomatal conductance; tonoplast; transgenic plant; water loss; adaptation; Arabidopsis; drought; drug effect; evapotranspiration; gene expression regulation; genetics; Hordeum; metabolism; physiological stress; plant leaf; plant stoma; signal transduction; soybean; tobacco; Vicia faba; Arabidopsis thaliana; Abscisic Acid; Adaptation, Physiological; Arabidopsis; Arabidopsis Proteins; Chloride Channels; Droughts; gamma-Aminobutyric Acid; Gene Expression Regulation, Plant; Glutamate Decarboxylase; Green Fluorescent Proteins; Hordeum; Isoenzymes; Plant Leaves; Plant Stomata; Plant Transpiration; Recombinant Fusion Proteins; Signal Transduction; Soybeans; Stress, Physiological; Tobacco; Vicia faba; Water
来源期刊	Nature Communications
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/251488
作者单位	Plant Transport and Signalling Lab, ARC Centre of Excellence in Plant Energy Biology, Waite Research Institute, Glen Osmond, SA, Australia; School of Agriculture, Food and Wine, Waite Research Precinct, University of Adelaide, Glen Osmond, SA, Australia; College of Horticulture, Nanjing Agricultural University, Nanjing, China; ARC Industrial Transformation Research Hub for Wheat in a Hot and Dry Climate, Waite Research Institute, University of Adelaide, Glen Osmond, SA, Australia; CSIRO Agriculture & Food, Glen Osmond, SA, Australia; Institute for Molecular Plant Physiology and Biophysics, University of Würzburg, Würzburg, Germany
推荐引用方式 GB/T 7714	Xu B.,Long Y.,Feng X.,et al. GABA signalling modulates stomatal opening to enhance plant water use efficiency and drought resilience[J],2021,12(1).
APA	Xu B..,Long Y..,Feng X..,Zhu X..,Sai N..,...&Gilliham M..(2021).GABA signalling modulates stomatal opening to enhance plant water use efficiency and drought resilience.Nature Communications,12(1).
MLA	Xu B.,et al."GABA signalling modulates stomatal opening to enhance plant water use efficiency and drought resilience".Nature Communications 12.1(2021).