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DOI10.1073/pnas.2115636118
Why sequence all eukaryotes?
Blaxter M.; Archibald J.M.; Childers A.K.; Coddington J.A.; Crandall K.A.; Di Palma F.; Durbin R.; Edwards S.V.; Graves J.A.M.; Hackett K.J.; Hall N.; Jarvis E.D.; Johnson R.N.; Karlsson E.K.; Kress W.J.; Kuraku S.; Lawniczak M.K.N.; Lindblad-Toh K.; Lopez J.V.; Moran N.A.; Robinson G.E.; Ryder O.A.; Shapiro B.; Soltis P.S.; Warnow T.; Zhang G.; Lewin H.A.
发表日期2022
ISSN0027-8424
卷号119期号:4
英文摘要Life on Earth has evolved from initial simplicity to the astounding complexity we experience today. Bacteria and archaea have largely excelled in metabolic diversification, but eukaryotes additionally display abundant morphological innovation. How have these innovations come about and what constraints are there on the origins of novelty and the continuing maintenance of biodiversity on Earth? The history of life and the code for the working parts of cells and systems are written in the genome. The Earth BioGenome Project has proposed that the genomes of all extant, named eukaryotes-about 2 million species-should be sequenced to high quality to produce a digital library of life on Earth, beginning with strategic phylogenetic, ecological, and high-impact priorities. Here we discuss why we should sequence all eukaryotic species, not just a representative few scattered across the many branches of the tree of life.We suggest that many questions of evolutionary and ecological significance will only be addressable when whole-genome data representing divergences at all of the branchings in the tree of life or all species in natural ecosystems are available. We envisage that a genomic tree of life will foster understanding of the ongoing processes of speciation, adaptation, and organismal dependencies within entire ecosystems. These explorations will resolve long-standing problems in phylogenetics, evolution, ecology, conservation, agriculture, bioindustry, and medicine. © 2022 National Academy of Sciences. All rights reserved.
英文关键词Conservation; Diversity; Ecology; Evolution; Genome
语种英语
scopus关键词agriculture; article; ecology; ecosystem; eukaryote; library; nonhuman; species differentiation; tree of life; phylogeny
来源期刊Proceedings of the National Academy of Sciences of the United States of America
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/250884
作者单位Wellcome Sanger Institute, Hinxton, Cambridge, CB10 1SA, United Kingdom; Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, NS B3H 4H7, Canada; Bee Research Laboratory, Agricultural Research Service, US Department of Agriculture (USDA), Beltsville, MD 20705, United States; Global Genome Initiative, National Museum of Natural History, Smithsonian Institution, Washington, DC 20560, United States; Computational Biology Institute, Department of Biostatistics and Bioinformatics, George Washington University, Washington, DC 20052, United States; Department of Invertebrate Zoology, Smithsonian Institution, Washington, DC 20013, United States; School of Biological Sciences, University of East Anglia, Norwich, NR4 7TJ, United Kingdom; Department of Genetics, University of Cambridge, Cambridge, CB2 3EH, United Kingdom; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, United States; Museum of Comparative Zoology, Harvard University, Cambr...
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GB/T 7714
Blaxter M.,Archibald J.M.,Childers A.K.,et al. Why sequence all eukaryotes?[J],2022,119(4).
APA Blaxter M..,Archibald J.M..,Childers A.K..,Coddington J.A..,Crandall K.A..,...&Lewin H.A..(2022).Why sequence all eukaryotes?.Proceedings of the National Academy of Sciences of the United States of America,119(4).
MLA Blaxter M.,et al."Why sequence all eukaryotes?".Proceedings of the National Academy of Sciences of the United States of America 119.4(2022).
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