气候变化领域集成服务门户(CCPortal): Associations between modeled residential outdoor and measured personal exposure to ultrafine particles in four European study areas

CCPortal

DOI	10.1016/j.atmosenv.2020.117353
	Associations between modeled residential outdoor and measured personal exposure to ultrafine particles in four European study areas
	van Nunen E.; Vermeulen R.; Tsai M.-Y.; Probst-Hensch N.; Ineichen A.; Imboden M.; Naccarati A.; Tarallo S.; Raffaele D.; Ranzi A.; Nieuwenhuijsen M.; Jarvis D.; Amaral A.F.; Vlaanderen J.; Meliefste K.; Brunekreef B.; Vineis P.; Gulliver J.; Hoek G.
发表日期	2020
ISSN	1352-2310
卷号	226
英文摘要	Land use regression (LUR) models for Ultrafine Particles (UFP) have been developed to assess health effects of long-term average UFP exposure in epidemiological studies. Associations between LUR modeled residential outdoor and measured long-term personal exposure to UFP have never been evaluated, adding uncertainty in interpretation of epidemiological studies of UFP. Our aim was to assess how predictions of recently developed LUR models for UFP compared to measured average personal UFP exposure in four European areas. Personal UFP exposure was measured in 154 adults from Basel (Switzerland), Amsterdam and Utrecht (the Netherlands), Norwich (United Kingdom), and Turin (Italy). Subjects performed three 24-h exposure measurements by carrying a real-time monitor measuring particles between 10 and 300 nm (MiniDisc). Subjects reported whereabouts and indoor sources of UFP in questionnaires. In Basel and the Netherlands contemporaneously residential outdoor UFP concentrations were monitored. Area-specific LUR models were applied to model residential outdoor UFP concentrations. Associations between modeled and measured UFP concentrations were assessed with linear regression. LUR model predictions were significantly associated with median but not mean personal UFP exposures, likely because of the high impact of indoor peaks on mean personal exposures. Regression slopes (±se) combined for the four areas were 0.12 ± 0.04 for median and −0.06 ± 0.17 for mean personal exposure. The LUR model explained variance of the median personal exposure less than variance of residential outdoor measurements. Associations did not change when personal exposure was calculated for the time spent at home or when presence of indoor sources was incorporated in the regression models. Regression slopes for measured residential outdoor versus personal exposure were smaller for UFP (0.16 ± 0.04) than for simultaneously measured PM2.5 and soot (0.32 ± 0.10 and 0.43 ± 0.06). Our findings provide some support for the use of LUR models to estimate long-term exposure to ambient generated UFP in epidemiological studies. © 2020 Elsevier Ltd
关键词	Exposure assessment Land use regression model Personal exposure Ultrafine particles
语种	英语
scopus关键词	Housing; Land use; Regression analysis; Surveys; Epidemiological studies; Exposure assessment; Exposure measurement; Land use regression; Land-use regression models; Outdoor measurements; Personal exposures; Ultrafine particle; Exposure controls; assessment method; concentration (composition); epidemiology; land use change; numerical model; particulate matter; pollution exposure; residential location; soot; adult; article; female; human; human experiment; Italy; land use; linear regression analysis; long term exposure; major clinical study; male; Netherlands; prediction; questionnaire; soot; Switzerland; United Kingdom; Amsterdam Island; Amsterdam [North Holland]; Basel; Basel-Stadt; England; French Southern Territories; Italy; Netherlands; Norfolk [England]; Norwich; Piedmont [Italy]; Switzerland; Switzerland; Torino [Piedmont]; Turin; United Kingdom; United Kingdom; Utrecht [Netherlands]
来源期刊	ATMOSPHERIC ENVIRONMENT
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/249242
作者单位	Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, Netherlands; Julius Center, University Medical Center Utrecht, Utrecht, Netherlands; Swiss Tropical and Public Health (TPH) Institute, University of Basel, Basel, Switzerland; University of Basel, Basel, Switzerland; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, United States; Italian Institute for Genomic Medicine (IIGM), Turin, Italy; Centre for Environmental Health and Prevention, Regional Agency for Environmental Protection and Energy of Emilia-Romagna, Modena, Italy; ISGlobal, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain; Department of Experimental and Health Sciences, Pompeu Fabra University (UPF), Barcelona, Spain; CIBER Epidemiologia y Salud Pública (CIBERESP), Barcelona, Spain; National Heart and Lung Institute, Imperial College London, London, United Kingdom; MRC Centre for Environment and Health, Department of Epidemiology and Biostati...
推荐引用方式 GB/T 7714	van Nunen E.,Vermeulen R.,Tsai M.-Y.,et al. Associations between modeled residential outdoor and measured personal exposure to ultrafine particles in four European study areas[J],2020,226.
APA	van Nunen E..,Vermeulen R..,Tsai M.-Y..,Probst-Hensch N..,Ineichen A..,...&Hoek G..(2020).Associations between modeled residential outdoor and measured personal exposure to ultrafine particles in four European study areas.ATMOSPHERIC ENVIRONMENT,226.
MLA	van Nunen E.,et al."Associations between modeled residential outdoor and measured personal exposure to ultrafine particles in four European study areas".ATMOSPHERIC ENVIRONMENT 226(2020).