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DOI | 10.1016/j.atmosenv.2021.118211 |
Short-term exposure to nitrogen dioxide and outpatient visits for cause-specific conjunctivitis: A time-series study in Jinan, China | |
Guo H.; Zhang S.; Zhang Z.; Zhang J.; Wang C.; Fang X.; Lin H.; Li H.; Ruan Z. | |
发表日期 | 2021 |
ISSN | 1352-2310 |
卷号 | 247 |
英文摘要 | Background: Though the conjunctiva are directly contacting with the atmospheric environment, the association between air pollution and conjunctival disease has not been well documented. Objective: To explore the association between ambient nitrogen dioxide (NO2) and daily outpatient visits for cause-specific conjunctivitis in Jinan, China. Methods: Daily concentrations of air pollution were obtained from the air quality sharing platform of China, and daily outpatient visits for conjunctivitis were collected from Qilu Hospital. The association between daily NO2 level and outpatient visits for conjunctivitis was examined by a generalized additive Poisson model, and stratified analyses by sex, age and season were further performed. Results: A total of 42,123 outpatient visits for conjunctivitis were recorded during 2014–2019, including 8504 infective conjunctivitis, 6429 allergic conjunctivitis and 27,190 unspecified conjunctivitis. Each 10 μg/m3 increase in NO2 was associated with a 1.00% (95% CI: 0.13%, 1.87%) increment in daily outpatient visits for conjunctivitis. Significant associations between NO2 and conjunctivitis were observed in the female population [excess risk, ER = 1.09% (95% CI: 0.05%, 2.15%)], in people aged 18–65 years [ER = 1.15% (95% CI: 0.15%, 2.15%)] and in cold season [ER = 1.67% (95% CI: 0.58%, 2.77%)]. Moreover, we also found significant associations of NO2 with infective conjunctivitis [ER = 2.60% (95% CI: 0.69%, 4.54%)], but not with allergic conjunctivitis [ER = −0.43% (95% CI: −2.38%, 1.56%)]and unspecified conjunctivitis [ER = 0.16% (95% CI: −0.96%, 1.29%)]. Conclusion: This study suggests that short-term exposure to NO2 might induce conjunctivitis, and air pollution control measures should be encouraged to keep ocular surface healthy. © 2021 Elsevier Ltd |
关键词 | Air pollutionConjunctivitisNitrogen dioxideShort-term exposureTime-series |
语种 | 英语 |
scopus关键词 | Air quality; Nitrogen oxides; Allergic conjunctivitis; Ambient nitrogen dioxide; Atmospheric environment; Generalized additives; Nitrogen dioxides; Sharing platforms; Short-term exposure; Stratified analysis; Air pollution control; nitrogen dioxide; ozone; sulfur dioxide; adult; aged; air pollution; air quality; allergic conjunctivitis; ambient air; Article; China; cold; conjunctivitis; controlled study; environmental exposure; female; high temperature; human; humidity; infective conjunctivitis; major clinical study; male; meteorological phenomena; outpatient care; particulate matter; pathogenesis; priority journal; time series analysis |
来源期刊 | ATMOSPHERIC ENVIRONMENT
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文献类型 | 期刊论文 |
条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/248604 |
作者单位 | Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan, 250012, China; Department of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, China; Editorial Department for Chinese Journal of Preventive Medicine, Chinese Medical Association Publishing House, Beijing, 100052, China; Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, 450001, China; Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, 230032, China; Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China |
推荐引用方式 GB/T 7714 | Guo H.,Zhang S.,Zhang Z.,et al. Short-term exposure to nitrogen dioxide and outpatient visits for cause-specific conjunctivitis: A time-series study in Jinan, China[J],2021,247. |
APA | Guo H..,Zhang S..,Zhang Z..,Zhang J..,Wang C..,...&Ruan Z..(2021).Short-term exposure to nitrogen dioxide and outpatient visits for cause-specific conjunctivitis: A time-series study in Jinan, China.ATMOSPHERIC ENVIRONMENT,247. |
MLA | Guo H.,et al."Short-term exposure to nitrogen dioxide and outpatient visits for cause-specific conjunctivitis: A time-series study in Jinan, China".ATMOSPHERIC ENVIRONMENT 247(2021). |
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