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DOI10.1016/j.atmosenv.2021.118563
On the airborne transmission of SARS-CoV-2 and relationship with indoor conditions at a hospital
Baboli Z.; Neisi N.; Babaei A.A.; Ahmadi M.; Sorooshian A.; Birgani Y.T.; Goudarzi G.
发表日期2021
ISSN1352-2310
卷号261
英文摘要The limited knowledge about the mechanism of SARS-CoV-2 transmission is a current challenge on a global scale. Among possible transmission routes, air transfer of the virus is thought to be prominent. To investigate this further, measurements were conducted at Razi hospital in Ahvaz, Iran, which was selected to treat COVID-19 severe cases in the Khuzestan province. Passive and active sampling methods were employed and compared with regard to their efficiency for collection of airborne SARS-COV-2 virus particles. Fifty one indoor air samples were collected in two areas, with distances of less than or equal to 1 m (patient room) and more than 3 m away (hallway and nurse station) from patient beds. A simulation method was used to obtain the virus load released by a regularly breathing or coughing individual including a range of microdroplet emissions. Using real-time reverse transcription polymerase chain reaction (RT-PCR), 11.76% (N = 6) of all indoor air samples (N = 51) collected in the COVID-19 ward tested positive for SARS-CoV-2 virus, including 4 cases in patient rooms and 2 cases in the hallway. Also, 5 of the 6 positive cases were confirmed using active sampling methods with only 1 based on passive sampling. The results support airborne transmission of SARS-CoV-2 bioaerosols in indoor air. Multivariate analysis showed that among 15 parameters studied, the highest correlations with PCR results were obtained for temperature, relative humidity, PM levels, and presence of an air cleaner. © 2021 Elsevier Ltd
关键词AerosolsAirborneIndoor air qualityRT-PCRSARS-CoV-2
语种英语
scopus关键词Aerosols; Air quality; Hospitals; Indoor air pollution; Multivariant analysis; Viruses; Active sampling; Air samples; Airborne; Airborne transmission; Indoor air; Indoor air quality; Passive sampling; Reverse transcription-polymerase chain reaction; Sampling method; SARS-CoV-2; Polymerase chain reaction; virus RNA; COVID-19; disease transmission; droplet; indoor air; polymerase chain reaction; real time; relative humidity; sampling; air sampling; airborne transmission; airway; Article; breathing; controlled study; coronavirus disease 2019; coughing; indoor environment; Iran; low temperature; mathematical model; nonhuman; nursing station; real time reverse transcription polymerase chain reaction; relative humidity; Severe acute respiratory syndrome coronavirus 2; simulation; virus concentration; virus load; Ahwaz; Iran; Khuzestan; SARS coronavirus
来源期刊ATMOSPHERIC ENVIRONMENT
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/248325
作者单位Student Research Committee, Department of Environmental Health Engineering, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Air Pollution and Respiratory Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Clinical Sciences Research Institute, Alimentary Tract Research Center, Department of Medical Virology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Department of Environmental Health Engineering, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Environmental Technologies Research Center (ETRC), Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Department of Chemical and Environmental Engineering, University of Arizona, Tucson, AZ, United States; Department of Hydrology and Atmospheric Sciences, University of Arizona, Tucson, AZ, United States
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Baboli Z.,Neisi N.,Babaei A.A.,et al. On the airborne transmission of SARS-CoV-2 and relationship with indoor conditions at a hospital[J],2021,261.
APA Baboli Z..,Neisi N..,Babaei A.A..,Ahmadi M..,Sorooshian A..,...&Goudarzi G..(2021).On the airborne transmission of SARS-CoV-2 and relationship with indoor conditions at a hospital.ATMOSPHERIC ENVIRONMENT,261.
MLA Baboli Z.,et al."On the airborne transmission of SARS-CoV-2 and relationship with indoor conditions at a hospital".ATMOSPHERIC ENVIRONMENT 261(2021).
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