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DOI | 10.1016/j.atmosenv.2021.118567 |
Ambient air pollution and out-of-hospital cardiac arrest. Israel nation wide assessment | |
Kranc H.; Novack V.; Shtein A.; Sonkin R.; Jaffe E.; Novack L. | |
发表日期 | 2021 |
ISSN | 1352-2310 |
卷号 | 261 |
英文摘要 | Introduction: Previous research suggested that an out-of-hospital cardiac arrest (OHCA) may be triggered by an exposure to ambient pollutants. Objective: We investigated the link between OHCA and a short-term exposure to particulate matter (PM) and other pollutants, within extreme climate conditions in Israel and high PM. Methods: In a case-crossover analysis, we analyzed all adult cases of OHCA in Israel during 2016–2017. The air-pollution and meteorology data were retrieved from the 132 monitoring stations. All associations at study were investigated using a lag-distributed regression and adjusted to temperature and humidity. Results: There were 12401 OHCA cases. Patients experiencing OHCA were likely to be exposed to elevated levels of pollutants, specifically, nitrogen dioxide (NO2) and particulate matter of size ≤2.5 μm (PM2.5) several hours prior to an event, although both at borderline significance, i.e. odds ratio (OR) = 1.20 (95%CI 0.96; 1.51) and OR = 1.15 (95%CI 0.84; 1.60), respectively. An exposure to NO2 was independently associated with OHCA among males (OR = 1.39, 95%CI 0.96; 2.01) and if occurred during the midweek (OR = 1.43, 95%CI 1.03; 1.97). The adverse effect of PM10 was more evident during a weekend (OR = 2.36, 95%CI 0.88; 6.28), as opposed to working days (OR = 0.81, 95%CI 0.45; 1.44). Analysis stratified by regions suggested a spatial variability in pollution associated with OHCA. Conclusions: Short-term exposure to high levels of pollution is adversely associated with OHCA independently of meteorological conditions. The magnitude of the effect is modified by patients' demography. Main finding: Short-term exposure to high levels of pollution is adversely associated with OHCA. This effect is independent of temperature and humidity. © 2021 The Authors |
关键词 | Air pollutionNO2OHCAPM10PM2.5SO2 |
语种 | 英语 |
scopus关键词 | Hospitals; Nitrogen oxides; Particles (particulate matter); Cardiac arrest; NO $-2$; Odd ratios; Out-of-hospital cardiac arrest; Particulate Matter; Particulate matter 10; Particulate matter2.5; Short-term exposure; SO$-2$; Temperature and humidities; Air pollution; nitrogen dioxide; ambient air; assessment method; atmospheric pollution; cardiology; climate conditions; nitrogen dioxide; particulate matter; pollution exposure; spatial variation; adverse event; aged; air pollutant; air pollution; ambient air; Article; climate; controlled study; demography; environmental exposure; female; human; humidity; Israel; major clinical study; male; out of hospital cardiac arrest; particulate matter 10; particulate matter 2.5; particulate matter exposure; temperature; Israel |
来源期刊 | ATMOSPHERIC ENVIRONMENT |
文献类型 | 期刊论文 |
条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/248322 |
作者单位 | Department of Emergency Medicine, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel; Clinical Research Center, Soroka University Medical Center, Beer Sheva, Israel; Department of Internal Medicine, Soroka University Medical Center, Beer Sheva, Israel; Department of Geography and Environmental Development, Faculty of Humanities and Social Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel; Community Division, Magen David Adom, Or-Yehuda, Israel; Blood Services Center, Magen David Adom, Tel-Aviv, Israel; Negev Environmental Health Research Institute, Soroka University Medical Center, Beer Sheva, Israel; Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel |
推荐引用方式 GB/T 7714 | Kranc H.,Novack V.,Shtein A.,et al. Ambient air pollution and out-of-hospital cardiac arrest. Israel nation wide assessment[J],2021,261. |
APA | Kranc H.,Novack V.,Shtein A.,Sonkin R.,Jaffe E.,&Novack L..(2021).Ambient air pollution and out-of-hospital cardiac arrest. Israel nation wide assessment.ATMOSPHERIC ENVIRONMENT,261. |
MLA | Kranc H.,et al."Ambient air pollution and out-of-hospital cardiac arrest. Israel nation wide assessment".ATMOSPHERIC ENVIRONMENT 261(2021). |
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