气候变化领域集成服务门户(CCPortal): Short-term air pollution exposure and exacerbation of psychosis: A case-crossover study in the capital city of South Korea

CCPortal

DOI	10.1016/j.atmosenv.2021.118836
	Short-term air pollution exposure and exacerbation of psychosis: A case-crossover study in the capital city of South Korea
	Lee W.; Byun S.; Jung J.; Kim H.; Ha T.H.; Myung W.; Lee H.
发表日期	2022
ISSN	1352-2310
卷号	269
英文摘要	There is a growing concern that air pollution exacerbates mental disorders. However, studies assessing the relationship between short-term exposure to ambient air pollution and acute exacerbation of psychotic symptoms in psychiatric disorders are limited. This study aims to examine the association between short-term air pollution exposure and acute exacerbation of psychosis in diverse psychiatric disorders. We analyzed 15,917 patients with psychosis (schizophrenia and related disorders and mood disorders with psychotic features) who visited Emergency Departments (EDs) in Seoul, South Korea, between 2008 and 2016. We estimated short-term exposures to particles <2.5 μm (PM2.5), particles <10 μm (PM10), nitrogen dioxide (NO2), sulfur dioxide (SO2), ozone (O3), and carbon monoxide (CO). We employed a conditional logistic regression with a time-stratified case-crossover design to compare the levels of ambient air pollution on ED visit days with those on control days. Results show that the risk of ED visits for psychosis was significantly associated with interquartile range increases in PM2.5 (Odds Ratio [OR] = 1.028; 95% Confidence Interval [CI]: 1.006, 1.049), PM10 (OR = 1.022; 95% CI: 1.003, 1.040), NO2 (OR = 1.037; 95% CI: 1.007, 1.068), and SO2 (OR = 1.030; 95% CI: 1.003, 1.058) in the best-fitting lags. Exposure to the highest quartile of air pollutants generally showed a higher risk for psychosis. The associations were higher among male patients, those with schizophrenia and related disorders, and in the cold season. This study provides new evidence that short-term exposure to elevated levels of air pollutants may increase the risk of acute exacerbation of psychosis. These findings could contribute to the development of policies for reducing air pollution levels and the presentation of psychoses. Further studies are warranted to elucidate our findings and explore the underlying mechanisms. © 2021 Elsevier Ltd
关键词	Air pollution Case-crossover analysis Emergency department visits Psychosis
语种	英语
scopus关键词	Carbon monoxide; Diseases; Emergency rooms; Nitrogen oxides; Sulfur dioxide; Acute exacerbations; Air pollution exposures; Case crossovers; Case-crossover analyse; Confidence interval; Emergency department visit; Emergency departments; Odd ratios; Psychosis; Short-term exposure; Air pollution; carbon monoxide; nitrogen dioxide; ozone; sulfur dioxide; ambient air; atmospheric pollution; capital city; disability; pollution exposure; adult; air pollution; ambient air; Article; cold stress; controlled study; crossover procedure; disease exacerbation; emergency ward; female; human; major clinical study; male; mood disorder; particulate matter 10; particulate matter 2.5; psychosis; season; short term exposure; South Korea; Seoul [South Korea]; South Korea
来源期刊	ATMOSPHERIC ENVIRONMENT
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/248121
作者单位	Department of Neuropsychiatry, Seoul National University Bundang Hospital, Bundang-gu, Seongnam, South Korea; Department of Neuropsychiatry, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of KoreaGyeonggi-do, South Korea; Data Management and Statistics Institute, Dongguk University Ilsan HospitalGyeonggi-do, South Korea; Department of Public Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, South Korea; Department of Psychiatry, Seoul National University, College of Medicine, Seoul, South Korea; Department of Health Administration and Management, College of Medical Sciences, Soonchunhyang University, Asan, South Korea; Department of Software Convergence, Soonchunhyang University Graduate School, Asan, South Korea
推荐引用方式 GB/T 7714	Lee W.,Byun S.,Jung J.,et al. Short-term air pollution exposure and exacerbation of psychosis: A case-crossover study in the capital city of South Korea[J],2022,269.
APA	Lee W..,Byun S..,Jung J..,Kim H..,Ha T.H..,...&Lee H..(2022).Short-term air pollution exposure and exacerbation of psychosis: A case-crossover study in the capital city of South Korea.ATMOSPHERIC ENVIRONMENT,269.
MLA	Lee W.,et al."Short-term air pollution exposure and exacerbation of psychosis: A case-crossover study in the capital city of South Korea".ATMOSPHERIC ENVIRONMENT 269(2022).