气候变化领域集成服务门户(CCPortal): Denisovan DNA in Late Pleistocene sediments from Baishiya Karst Cave on the Tibetan Plateau

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DOI	10.1126/SCIENCE.ABB6320
	Denisovan DNA in Late Pleistocene sediments from Baishiya Karst Cave on the Tibetan Plateau
	Zhang D.; Xia H.; Chen F.; Li B.; Slon V.; Cheng T.; Yang R.; Jacobs Z.; Dai Q.; Massilani D.; Shen X.; Wang J.; Feng X.; Cao P.; Yang M.A.; Yao J.; Yang J.; Madsen D.B.; Han Y.; Ping W.; Liu F.; Perreault C.; Chen X.; Meyer M.; Kelso J.; Pääbo S.; Fu Q.
发表日期	2020
ISSN	0036-8075
起始页码	584
结束页码	587
卷号	370 期号:6516
英文摘要	A late Middle Pleistocene mandible from Baishiya Karst Cave (BKC) on the Tibetan Plateau has been inferred to be from a Denisovan, an Asian hominin related to Neanderthals, on the basis of an amino acid substitution in its collagen. Here we describe the stratigraphy, chronology, and mitochondrial DNA extracted from the sediments in BKC. We recover Denisovan mitochondrial DNA from sediments deposited ~100 thousand and ~60 thousand years ago (ka) and possibly as recently as ~45 ka. The long-term occupation of BKC by Denisovans suggests that they may have adapted to life at high altitudes and may have contributed such adaptations to modern humans on the Tibetan Plateau. © 2020 American Association for the Advancement of Science. All rights reserved.
英文关键词	mitochondrial DNA; ancient DNA; mitochondrial DNA; amino acid; cave; DNA; hominid; karst; mitochondrial DNA; Neanderthal; occupation; Pleistocene; sediment analysis; altitude; Article; chronology; DNA sequence; evolutionary adaptation; Homo denisovan; Homo neanderthalensis; human; nucleic acid base substitution; phylogenetic tree; priority journal; sediment; stratigraphy; Tibet; Upper Pleistocene; animal; cave; chemistry; classification; genetics; hominid; isolation and purification; phylogeny; sediment; China; Qinghai-Xizang Plateau; Animals; Caves; DNA, Ancient; DNA, Mitochondrial; Geologic Sediments; Hominidae; Humans; Phylogeny; Tibet
语种	英语
来源期刊	Science
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/246146
作者单位	Key Laboratory of Western China’s Environmental Systems (Ministry of Education), College of Earth and Environmental Sciences, Lanzhou University, Lanzhou, 730000, China; Key Laboratory of Alpine Ecology (LAE), CAS Center for Excellence in Tibetan Plateau Earth Sciences, Institute of Tibetan Plateau Research, Chinese Academy of Sciences (CAS), Beijing, 100101, China; Frontier Center for Eco-environment and Climate Change in Pan-third Pole Regions, Lanzhou University, Lanzhou, 730000, China; Centre for Archaeological Science, School of Earth, Atmospheric and Life Sciences, University of Wollongong, Wollongong, NSW 2522, Australia; Australian Research Council (ARC) Centre of Excellence for Australian Biodiversity and Heritage, University of Wollongong, Wollongong, NSW 2522, Australia; Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, 04103, Germany; Key Laboratory of Vertebrate Evolution and Human Origins of Chinese Academy of Sciences, Institute of Vertebrat...
推荐引用方式 GB/T 7714	Zhang D.,Xia H.,Chen F.,et al. Denisovan DNA in Late Pleistocene sediments from Baishiya Karst Cave on the Tibetan Plateau[J],2020,370(6516).
APA	Zhang D..,Xia H..,Chen F..,Li B..,Slon V..,...&Fu Q..(2020).Denisovan DNA in Late Pleistocene sediments from Baishiya Karst Cave on the Tibetan Plateau.Science,370(6516).
MLA	Zhang D.,et al."Denisovan DNA in Late Pleistocene sediments from Baishiya Karst Cave on the Tibetan Plateau".Science 370.6516(2020).