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DOI10.1126/science.7112124
Living with water stress: Evolution of osmolyte systems
Yancey P.H.; Clark M.E.; Hand S.C.; Bowlus R.D.; Somero G.N.
发表日期1982
ISSN0036-8075
起始页码1214
结束页码1222
卷号217期号:4566
英文摘要Striking convergent evolution is found in the properties of the organic osmotic solute (osmolyte) systems observed in bacteria, plants, and animals. Polyhydric alcohols, free amino acids and their derivatives, and combinations of urea and methylamines are the three types of osmolyte systems found in all water-stressed organisms except the halobacteria. The selective advantages of the organic osmolyte systems are, first, a compatibility with macromolecular structure and function at high or variable (or both) osmolyte concentrations, and, second, greatly reduced needs for modifying proteins to function in concentrated intracellular solutions. Osmolyte compatibility is proposed to result from the absence of osmolyte interactions with substrates and cofactors, and the nonperturbing or favorable effects of osmolytes on macromolecular- solvent interactions. Copyright © 1982 AAAS.
英文关键词amino acid; glycerol; ion; methylamine; urea; water; active transport; animal; article; conformation; electrolyte balance; evolution; physiology; Amino Acids; Animal; Biological Transport, Active; Evolution; Glycerol; Ions; Methylamines; Molecular Conformation; Support, U.S. Gov't, Non-P.H.S.; Urea; Water; Water-Electrolyte Balance
语种英语
来源期刊Science
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/246087
作者单位Department of Biology, Whitman College, Walla Walla, WA 99362, United States; Department of Biology, San Diego State University, San Diego, CA 92182, United States; Department of Biology, University of Southwestern Louisiana, Lafayette, LA 70504, United States; Harvard School, Los Angeles, CA 91604, United States; Department of Biology, Scripps Institution of Oceanography, University of California, San Diego, CA 92093, United States
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GB/T 7714
Yancey P.H.,Clark M.E.,Hand S.C.,et al. Living with water stress: Evolution of osmolyte systems[J],1982,217(4566).
APA Yancey P.H.,Clark M.E.,Hand S.C.,Bowlus R.D.,&Somero G.N..(1982).Living with water stress: Evolution of osmolyte systems.Science,217(4566).
MLA Yancey P.H.,et al."Living with water stress: Evolution of osmolyte systems".Science 217.4566(1982).
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