气候变化领域集成服务门户(CCPortal): Global trends in antimicrobial resistance in animals in low- And middle-income countries

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DOI	10.1126/science.aaw1944
	Global trends in antimicrobial resistance in animals in low- And middle-income countries
	Van Boeckel T.P.; Pires J.; Silvester R.; Zhao C.; Song J.; Criscuolo N.G.; Gilbert M.; Bonhoeffer S.; Laxminarayan R.
发表日期	2019
ISSN	0036-8075
卷号	365 期号:6459
英文摘要	The global scale-up in demand for animal protein is the most notable dietary trend of our time. Antimicrobial consumption in animals is threefold that of humans and has enabled large-scale animal protein production. The consequences for the development of antimicrobial resistance in animals have received comparatively less attention than in humans. We analyzed 901 point prevalence surveys of pathogens in developing countries to map resistance in animals. China and India represented the largest hotspots of resistance, with new hotspots emerging in Brazil and Kenya. From 2000 to 2018, the proportion of antimicrobials showing resistance above 50% increased from 0.15 to 0.41 in chickens and from 0.13 to 0.34 in pigs. Escalating resistance in animals is anticipated to have important consequences for animal health and, eventually, for human health. Copyright © 2019 The Authors,
英文关键词	animal community; antimicrobial activity; disease prevalence; global change; pathogen; protein; trend analysis; animal experiment; animal health; antibiotic resistance; article; Brazil; chicken; China; developing country; India; infectious agent; Kenya; middle income country; nonhuman; pig; prevalence; animal; Campylobacter; drug effect; Escherichia coli; livestock; microbiology; Salmonella; Staphylococcus aureus; Brazil; China; India; Kenya; Animalia; Gallus gallus; Suidae; antiinfective agent; veterinary drug; Animals; Anti-Infective Agents; Brazil; Campylobacter; Chickens; China; Developing Countries; Drug Resistance, Bacterial; Escherichia coli; India; Kenya; Livestock; Prevalence; Salmonella; Staphylococcus aureus; Sus scrofa; Veterinary Drugs
语种	英语
来源期刊	Science
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/245818
作者单位	Institute for Environmental Decisions, ETH Zurich, Zurich, Switzerland; Center for Disease Dynamics, Economics and Policy, New Delhi, India; Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, United States; Princeton Environmental Institute, Princeton University, Princeton, NJ, United States; Université Libre de Bruxelles (ULB), Brussels, Belgium; Institute for Integrative Biology, ETH Zurich, Zurich, Switzerland
推荐引用方式 GB/T 7714	Van Boeckel T.P.,Pires J.,Silvester R.,et al. Global trends in antimicrobial resistance in animals in low- And middle-income countries[J],2019,365(6459).
APA	Van Boeckel T.P..,Pires J..,Silvester R..,Zhao C..,Song J..,...&Laxminarayan R..(2019).Global trends in antimicrobial resistance in animals in low- And middle-income countries.Science,365(6459).
MLA	Van Boeckel T.P.,et al."Global trends in antimicrobial resistance in animals in low- And middle-income countries".Science 365.6459(2019).