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DOI10.1126/science.aau4679
The challenge of antimicrobial resistance: What economics can contribute
Roope L.S.J.; Smith R.D.; Pouwels K.B.; Buchanan J.; Abel L.; Eibich P.; Butler C.C.; Tan P.S.; Sarah Walker A.; Robotham J.V.; Wordsworth S.
发表日期2019
ISSN0036-8075
卷号364期号:6435
英文摘要As antibiotic consumption grows, bacteria are becoming increasingly resistant to treatment. Antibiotic resistance undermines much of modern health care, which relies on access to effective antibiotics to prevent and treat infections associated with routine medical procedures. The resulting challenges have much in common with those posed by climate change, which economists have responded to with research that has informed and shaped public policy. Drawing on economic concepts such as externalities and the principal–agent relationship, we suggest how economics can help to solve the challenges arising from increasing resistance to antibiotics. We discuss solutions to the key economic issues, from incentivizing the development of effective new antibiotics to improving antibiotic stewardship through financial mechanisms and regulation. © 2017 The Authors.
英文关键词antibiotic agent; new drug; antiinfective agent; antibiotic resistance; antibiotics; antimicrobial activity; bacterium; climate change; disease treatment; health care; antibiotic resistance; antimicrobial stewardship; climate change; drug efficacy; drug synthesis; drug use; economic aspect; financial management; health care access; health care policy; health care system; health economics; human; infection; infection prevention; medical information; medical procedures; morbidity; mortality; priority journal; public health service; Review; socioeconomics; animal; bacterium; drug development; drug effect; economics; health care delivery; social control; Animals; Anti-Bacterial Agents; Antimicrobial Stewardship; Bacteria; Climate Change; Delivery of Health Care; Drug Development; Drug Resistance, Bacterial; Economics; Humans; Social Control, Formal
语种英语
来源期刊Science
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/245273
作者单位Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, United Kingdom; National Institute for Health Research (NIHR), Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, University of Oxford, Oxford, United Kingdom; NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom; University of Exeter Medical School, St Luke’s Campus, Exeter, United Kingdom; Modelling and Economics Unit, National Infection Service, Public Health England, London, United Kingdom; Department of Health Sciences, Global Health, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom; Max Planck Institute for Demographic Research, Rostock, Germany; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Nuffield Department of Medic...
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Roope L.S.J.,Smith R.D.,Pouwels K.B.,et al. The challenge of antimicrobial resistance: What economics can contribute[J],2019,364(6435).
APA Roope L.S.J..,Smith R.D..,Pouwels K.B..,Buchanan J..,Abel L..,...&Wordsworth S..(2019).The challenge of antimicrobial resistance: What economics can contribute.Science,364(6435).
MLA Roope L.S.J.,et al."The challenge of antimicrobial resistance: What economics can contribute".Science 364.6435(2019).
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