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DOI10.1126/science.abf0874
Resurgence of SARS-CoV-2: Detection by community viral surveillance
Riley S.; Ainslie K.E.C.; Eales O.; Walters C.E.; Wang H.; Atchison C.; Fronterre C.; Diggle P.J.; Ashby D.; Donnelly C.A.; Cooke G.; Barclay W.; Ward H.; Darzi A.; Elliott P.
发表日期2021
ISSN0036-8075
起始页码990
结束页码995
卷号372期号:6545
英文摘要Surveillance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has mainly relied on case reporting, which is biased by health service performance, test availability, and test-seeking behaviors. We report a community-wide national representative surveillance program in England based on self-administered swab results from ~594,000 individuals tested for SARS-CoV-2, regardless of symptoms, between May and the beginning of September 2020. The epidemic declined between May and July 2020 but then increased gradually from mid-August, accelerating into early September 2020 at the start of the second wave. When compared with cases detected through routine surveillance, we report here a longer period of decline and a younger age distribution. Representative community sampling for SARS-CoV-2 can substantially improve situational awareness and feed into the public health response even at low prevalence. © 2021 American Association for the Advancement of Science. All rights reserved.
英文关键词disease severity; epidemic; health services; public health; severe acute respiratory syndrome; adult; age distribution; Article; basic reproduction number; clinical effectiveness; community transmission; community viral surveillance; controlled study; coronavirus disease 2019; disease surveillance; England; epidemic; epidemic doubling time; epidemiological data; ethnic difference; groups by age; halving time; hospitalization; human; infection sensitivity; major clinical study; middle aged; mortality; nasopharyngeal swab; nonhuman; prevalence; priority journal; seroprevalence; Severe acute respiratory syndrome coronavirus 2; social distancing; swabbing; trend study; vaccination; virus detection; virus transmission; young adult; adolescent; aged; child; diagnosis; epidemiological monitoring; epidemiology; female; health survey; male; pandemic; preschool child; England; United Kingdom; SARS coronavirus; Adolescent; Adult; Aged; Basic Reproduction Number; Child; Child, Preschool; COVID-19; COVID-19 Nucleic Acid Testing; England; Epidemiological Monitoring; Female; Humans; Male; Middle Aged; Pandemics; Prevalence; Public Health Surveillance; SARS-CoV-2; Young Adult
语种英语
来源期刊Science
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/245227
作者单位School of Public Health, Imperial College London, London, United Kingdom; MRC Centre for Global Infectious Disease Analysis, Abdul Latif Jameel Institute for Disease and Emergency Analytics, Imperial College London, London, United Kingdom; Centre for Health Informatics, Computing, and Statistics (CHICAS), Lancaster Medical School, Lancaster University, Lancaster, United Kingdom; Health Data Research UK, London, United Kingdom; Department of Statistics, University of Oxford, Oxford, United Kingdom; Department of Infectious Disease, Imperial College London, London, United Kingdom; Imperial College Healthcare NHS Trust, London, United Kingdom; National Institute for Health Research Imperial Biomedical Research Centre, London, United Kingdom; Institute of Global Health Innovation, Imperial College London, London, United Kingdom; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, United Kingdom
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Riley S.,Ainslie K.E.C.,Eales O.,et al. Resurgence of SARS-CoV-2: Detection by community viral surveillance[J],2021,372(6545).
APA Riley S..,Ainslie K.E.C..,Eales O..,Walters C.E..,Wang H..,...&Elliott P..(2021).Resurgence of SARS-CoV-2: Detection by community viral surveillance.Science,372(6545).
MLA Riley S.,et al."Resurgence of SARS-CoV-2: Detection by community viral surveillance".Science 372.6545(2021).
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