Climate Change Data Portal
| DOI | 10.1126/science.abb6460 |
| The evolutionary history of Neanderthal and Denisovan Y chromosomes | |
| Petr M.; Hajdinjak M.; Fu Q.; Essel E.; Rougier H.; Crevecoeur I.; Semal P.; Golovanova L.V.; Doronichev V.B.; Lalueza-Fox C.; De la Rasilla M.; Rosas A.; Shunkov M.V.; Kozlikin M.B.; Derevianko A.P.; Vernot B.; Meyer M.; Kelso J. | |
| 发表日期 | 2020 |
| ISSN | 0036-8075 |
| 卷号 | 369期号:6511 |
| 英文摘要 | Ancient DNA has provided new insights into many aspects of human history. However, we lack comprehensive studies of the Y chromosomes of Denisovans and Neanderthals because the majority of specimens that have been sequenced to sufficient coverage are female. Sequencing Y chromosomes from two Denisovans and three Neanderthals shows that the Y chromosomes of Denisovans split around 700 thousand years ago from a lineage shared by Neanderthals and modern human Y chromosomes, which diverged from each other around 370 thousand years ago. The phylogenetic relationships of archaic and modern human Y chromosomes differ from the population relationships inferred from the autosomal genomes and mirror mitochondrial DNA phylogenies, indicating replacement of both the mitochondrial and Y chromosomal gene pools in late Neanderthals. This replacement is plausible if the low effective population size of Neanderthals resulted in an increased genetic load in Neanderthals relative to modern humans. © 2020 American Association for the Advancement of Science. All rights reserved. |
| 英文关键词 | mitochondrial DNA; ancient DNA; mitochondrial DNA; chromosome; effective population size; evolutionary theory; mitochondrial DNA; Neanderthal; type specimen; Article; consensus; DNA damage; evolution; gene deletion; gene flow; gene locus; gene mutation; genetic load; genetic variation; genome; genotype; Homo denisovan; Homo neanderthalensis; human; phylogeny; priority journal; RNA sequencing; single nucleotide polymorphism; Y chromosome; animal; classification; genetics; life history trait; male; molecular evolution; Y chromosome; Animals; Chromosomes, Human, Y; DNA, Ancient; DNA, Mitochondrial; Evolution, Molecular; Humans; Life History Traits; Male; Neanderthals; Phylogeny; Y Chromosome |
| 语种 | 英语 |
| 来源期刊 | Science
 |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/245067 |
| 作者单位 | Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, D-04103, Germany; Francis Crick Institute, London, NW1 1AT, United Kingdom; Key Laboratory of Vertebrate Evolution and Human Origins of Chinese Academy of Sciences, IVPP, CAS, Beijing, 100044, China; CAS Center for Excellence in Life and Paleoenvironment, Beijing, 100044, China; University of Chinese Academy of Sciences, Beijing, 100049, China; Department of Anthropology, California State University, Northridge, Northridge, CA 91330-8244, United States; Université de Bordeaux, CNRS, UMR 5199-PACEA, Pessac Cedex, 33615, France; Royal Belgian Institute of Natural Sciences, Brussels, 1000, Belgium; ANO Laboratory of Prehistory 14 Linia 3-11, St. Petersburg, 1990 34, Russian Federation; Institute of Evolutionary Biology, Consejo Superior de Investigaciones Científicas, Universitat Pompeu Fabra, Barcelona, 08003, Spain; Área de Prehistoria, Departamento de Historia, Universidad de Oviedo, Oviedo, 33011, Spain; De... |
| 推荐引用方式 GB/T 7714 | Petr M.,Hajdinjak M.,Fu Q.,et al. The evolutionary history of Neanderthal and Denisovan Y chromosomes[J],2020,369(6511). |
| APA | Petr M..,Hajdinjak M..,Fu Q..,Essel E..,Rougier H..,...&Kelso J..(2020).The evolutionary history of Neanderthal and Denisovan Y chromosomes.Science,369(6511). |
| MLA | Petr M.,et al."The evolutionary history of Neanderthal and Denisovan Y chromosomes".Science 369.6511(2020). |
| 条目包含的文件 | 条目无相关文件。 | |||||
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
