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DOI10.1126/science.abe8372originally
Age groups that sustain resurging COVID-19 epidemics in the United States
Monod M.; Blenkinsop A.; Xi X.; Hebert D.; Bershan S.; Tietze S.; Baguelin M.; Bradley V.C.; Chen Y.; Coupland H.; Filippi S.; Ish-Horowicz J.; McManus M.; Mellan T.; Gandy A.; Hutchinson M.; Unwin J.H.T.; van Elsland S.L.; Vollmer M.A.C.; Weber S.; Zhu H.; Bezancon A.; Ferguson N.M.; Mishra S.; Flaxman S.; Bhatt S.; Ratmann O.; the Imperial College COVID-19 Response Team
发表日期2021
ISSN0036-8075
卷号371期号:6536
英文摘要After initial declines, in mid-2020 a resurgence in transmission of novel coronavirus disease (COVID-19) occurred in the United States and Europe. As efforts to control COVID-19 disease are reintensified, understanding the age demographics driving transmission and how these affect the loosening of interventions is crucial. We analyze aggregated, age-specific mobility trends from more than 10 million individuals in the United States and link these mechanistically to age-specific COVID-19 mortality data. We estimate that as of October 2020, individuals aged 20 to 49 are the only age groups sustaining resurgent SARS-CoV-2 transmission with reproduction numbers well above one and that at least 65 of 100 COVID-19 infections originate from individuals aged 20 to 49 in the United States. Targeting interventions-including transmission-blocking vaccines-to adults aged 20 to 49 is an important consideration in halting resurgent epidemics and preventing COVID-19-attributable deaths. © 2021 American Association for the Advancement of Science. All rights reserved.
英文关键词COVID-19; disease control; epidemic; infectious disease; infectivity; mortality; age distribution; Article; cell phone use; contact examination; coronavirus disease 2019; disease association; disease course; disease transmission; epidemic; geographic distribution; health program; human; infection control; infection risk; molecular dynamics; mortality rate; nonhuman; priority journal; return to school; summer; United States; Europe; United States; Coronavirus; SARS coronavirus
语种英语
来源期刊Science
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/244803
作者单位Department of Mathematics, Imperial College London, London, United Kingdom; Foursquare Inc., New York, NY, United States; Emodo, San Francisco, CA, United States; MRC Centre for Global Infectious Disease Analysis, The Abdul Latif Jameel Institute for Disease and Emergency Analytics (J-IDEA), School of Public Health, Imperial College London, London, United Kingdom; Department of Statistics, University of Oxford, Oxford, United Kingdom; Novartis Pharma AG, Basel, Switzerland; Section of Epidemiology, Department of Public Health, University of Copenhagen, Denmark
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Monod M.,Blenkinsop A.,Xi X.,et al. Age groups that sustain resurging COVID-19 epidemics in the United States[J],2021,371(6536).
APA Monod M..,Blenkinsop A..,Xi X..,Hebert D..,Bershan S..,...&the Imperial College COVID-19 Response Team.(2021).Age groups that sustain resurging COVID-19 epidemics in the United States.Science,371(6536).
MLA Monod M.,et al."Age groups that sustain resurging COVID-19 epidemics in the United States".Science 371.6536(2021).
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