气候变化领域集成服务门户(CCPortal): Age groups that sustain resurging COVID-19 epidemics in the United States

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DOI	10.1126/SCIENCE.ABE8372
	Age groups that sustain resurging COVID-19 epidemics in the United States
	Monod M.; Blenkinsop A.; Xi X.; Hebert D.; Bershan S.; Tietze S.; Baguelin M.; Bradley V.C.; Chen Y.; Coupland H.; Filippi S.; Ish-Horowicz J.; McManus M.; Mellan T.; Gandy A.; Hutchinson M.; Unwin H.J.T.; van Elsland S.L.; Vollmer M.A.C.; Weber S.; Zhu H.; Bezancon A.; Ferguson N.M.; Mishra S.; Flaxman S.; Bhatt S.; Ratmann O.; Imperial College COVID-19 Response Team
发表日期	2021
ISSN	0036-8075
卷号	371 期号:6536
英文摘要	After initial declines, in mid-2020 a resurgence in transmission of novel coronavirus disease (COVID-19) occurred in the United States and Europe. As efforts to control COVID-19 disease are reintensified, understanding the age demographics driving transmission and how these affect the loosening of interventions is crucial. We analyze aggregated, age-specific mobility trends from more than 10 million individuals in the United States and link these mechanistically to age-specific COVID-19 mortality data. We estimate that as of October 2020, individuals aged 20 to 49 are the only age groups sustaining resurgent SARS-CoV-2 transmission with reproduction numbers well above one and that at least 65 of 100 COVID-19 infections originate from individuals aged 20 to 49 in the United States. Targeting interventions-including transmission-blocking vaccines-to adults aged 20 to 49 is an important consideration in halting resurgent epidemics and preventing COVID-19-attributable deaths. © 2021 American Association for the Advancement of Science. All rights reserved.
英文关键词	SARS-CoV-2 vaccine; COVID-19; demography; disease transmission; epidemic; mortality; reproduction; spatiotemporal analysis; viral disease; adult; age; Article; basic reproduction number; contact examination; coronavirus disease 2019; epidemic; human; infection control; infection prevention; middle aged; mortality rate; priority journal; school reentry; Severe acute respiratory syndrome coronavirus 2; social distancing; trend study; United States; virus transmission; young adult; adolescent; age; child; communicable disease control; epidemic; epidemiology; infant; mobile phone; mortality; pandemic; preschool child; prevention and control; school; theoretical model; United States; Europe; United States; Coronavirus; SARS coronavirus; Adolescent; Adult; Age Factors; Basic Reproduction Number; Cell Phone; Child; Child, Preschool; Communicable Disease Control; COVID-19; COVID-19 Vaccines; Epidemics; Humans; Infant; Middle Aged; Models, Theoretical; Pandemics; Schools; United States; Young Adult
语种	英语
来源期刊	Science
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/244802
作者单位	Department of Mathematics, Imperial College London, London, United Kingdom; Foursquare Inc., New York, NY, United States; Emodo, San Francisco, CA, United States; MRC Centre for Global Infectious Disease Analysis, Abdul Latif Jameel Institute for Disease and Emergency Analytics (J-IDEA), School of Public Health, Imperial College London, London, United Kingdom; Department of Statistics, University of Oxford, Oxford, United Kingdom; Novartis Pharma AG, Basel, Switzerland; Section of Epidemiology, Department of Public Health, University of Copenhagen, Denmark
推荐引用方式 GB/T 7714	Monod M.,Blenkinsop A.,Xi X.,et al. Age groups that sustain resurging COVID-19 epidemics in the United States[J],2021,371(6536).
APA	Monod M..,Blenkinsop A..,Xi X..,Hebert D..,Bershan S..,...&Imperial College COVID-19 Response Team.(2021).Age groups that sustain resurging COVID-19 epidemics in the United States.Science,371(6536).
MLA	Monod M.,et al."Age groups that sustain resurging COVID-19 epidemics in the United States".Science 371.6536(2021).