气候变化领域集成服务门户(CCPortal): A sense of space in postrhinal cortex

CCPortal

DOI	10.1126/science.aax4192
	A sense of space in postrhinal cortex
	LaChance P.A.; Todd T.P.; Taube J.S.
发表日期	2019
ISSN	0036-8075
卷号	365 期号:6449
英文摘要	A topographic representation of local space is critical for navigation and spatial memory. In humans, topographic spatial learning relies upon the parahippocampal cortex, damage to which renders patients unable to navigate their surroundings or develop new spatial representations. Stable spatial signals have not yet been observed in its rat homolog, the postrhinal cortex. We recorded from single neurons in the rat postrhinal cortex whose firing reflects an animal’s egocentric relationship to the geometric center of the local environment, as well as the animal’s head direction in an allocentric reference frame. Combining these firing correlates revealed a population code for a stable topographic map of local space. This may form the basis for higher-order spatial maps such as those seen in the hippocampus and entorhinal cortex. © 2019 American Association for the Advancement of Science. All rights reserved.
英文关键词	brain; correlation; learning; map; memory; topography; adult; animal experiment; article; entorhinal cortex; female; head; hippocampus; male; nerve cell; nonhuman; parahippocampal gyrus; rat; spatial learning; spatial memory; animal; Long Evans cinnamon rat; physiology; spatial orientation; Rattus; Animals; Entorhinal Cortex; Female; Neurons; Rats; Rats, Inbred LEC; Spatial Memory; Spatial Navigation
语种	英语
来源期刊	Science
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/244431
作者单位	Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH, United States
推荐引用方式 GB/T 7714	LaChance P.A.,Todd T.P.,Taube J.S.. A sense of space in postrhinal cortex[J],2019,365(6449).
APA	LaChance P.A.,Todd T.P.,&Taube J.S..(2019).A sense of space in postrhinal cortex.Science,365(6449).
MLA	LaChance P.A.,et al."A sense of space in postrhinal cortex".Science 365.6449(2019).