气候变化领域集成服务门户(CCPortal): Ten millennia of hepatitis B virus evolution

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DOI	10.1126/science.abi5658
	Ten millennia of hepatitis B virus evolution
	Kocher A.; Papac L.; Barquera R.; Key F.M.; Spyrou M.A.; Hübler R.; Rohrlach2 A.B.; Aron F.; Stahl R.; Wissgott A.; Van Bömme F.; Pfefferkorn M.; Alissa M.; Villalba-Mouco V.; Neumann G.U.; Rivollat M.; Van De Loosdrecht M.S.; Majander K.; Tukhbatova R.I.; Musralina L.; Ghalichi A.; Penske S.; Sabin S.; Michel M.; Gretzinger J.; Nelson E.A.; Ferraz T.; Nägele K.; Parker C.; Keller M.; Guevara E.K.; Feldman M.; Eisenmann S.; Skourtanioti E.; Giffin K.; Gnecchi-Ruscone G.A.; Friederich S.; Schimmenti V.; Khartanovich V.; Karapetian M.K.; Chaplygin M.S.; Kufterin V.V.; Khokhlov A.A.; Chizhevsky A.A.; Stashenkov D.A.; Kochkina A.F.; Tejedor-Rodríguez C.; De Lagrán Í.G.-M.; Arcusa-Magallón H.; Garrido-Pena R.; Royo-Guillén J.I.; Nováček J.; Rottier S.; Kacki S.; Saintot S.; Kaverzneva E.; Belinskiy A.B.; Velemínský P.; Limburský P.; Kostka M.; Loe L.; Popescu E.; Clarke R.; Lyons A.; Mortimer R.; Sajantila A.; Armas Y.C.D.; Godoy S.T.H.; Hernández-Zaragoza D.I.; Pearson J.; Binder D.; Lefranc P.; Kantorovich A.R.; Maslov V.E.; Lai L.; Zoledziewska M.; Beckett J.F.; Langová M.; Danielisová A.; Ingman T.; Atiénzar G.G.; Ibáñez M.P.D.M.; Romero A.; Sperduti A.; Beckett S.; Salter S.J.; Zilivinskaya E.D.; Vasil'ev D.V.; Heyking K.V.; Burger R.L.; Salazar L.C.; Amkreutz L.; Navruzbekov M.; Rosenstock E.; Alonso-Fernández C.; Slavchev V.; Kalmykov A.A.; Atabiev B.Ch.; Batieva E.; Calmet M.A.; Llamas B.; Schultz M.; Krauß R.; Jiménez-Echevarría J.; Francken M.; Shnaider S.; Knijff P.D.; Altena E.; Vijver K.V.D.; Fehren-Schmitz L.; Tung T.A.; Lösch S.; Dobrovolskaya M.; Makarov N.; Read C.; Twest M.V.; Sagona C.; Ramsl P.C.; Akar M.; Yener K.A.; Ballestero E.C.; Cucca F.; Mazzarello V.; Utrilla P.; Rademaker K.; Fernández-Domínguez E.; Baird D.; Semal P.; Márquez-Morfín L.; Roksandic M.; Steiner H.; Salazar-García D.C.; Shishlina N.; Erdal Y.S.; Hallgren F.; Boyadzhiev Y.; Boyadzhiev K.; Küßner M.; Sayer D.; Onkamo P.; Skeates R.; Rojo-Guerra M.; Buzhilova A.; Khussainova E.; Djansugurova L.B.; Beisenov A.Z.; Samashev Z.; Massy K.; Mannino M.; Moiseyev V.; Mannermaa K.; Balanovsky O.; Deguilloux M.-F.; Reinhold S.; Hansen S.; Kitov E.P.; Dobeš M.; Ernée M.; Meller H.; Kurt A.W.; Prüfer K.; Warinner C.; Schiffels S.; Stockhammer P.W.; Bos K.; Posth C.; Herbig A.; Haak W.; Krause2 J.; Krause2 J.; Kocher A.
发表日期	2021
ISSN	0036-8075
卷号	374 期号:6564
英文摘要	Hepatitis B virus (HBV) has been infecting humans for millennia and remains a global health problem, but its past diversity and dispersal routes are largely unknown. We generated HBV genomic data from 137 Eurasians and Native Americans dated between ~10,500 and ~400 years ago. We date the most recent common ancestor of all HBV lineages to between ~20,000 and 12,000 years ago, with the virus present in European and South American hunter-gatherers during the early Holocene. After the European Neolithic transition, Mesolithic HBV strains were replaced by a lineage likely disseminated by early farmers that prevailed throughout western Eurasia for ~4000 years, declining around the end of the 2nd millennium BCE. The only remnant of this prehistoric HBV diversity is the rare genotype G, which appears to have reemerged during the HIV pandemic. © 2021 American Association for the Advancement of Science. All rights reserved.
英文关键词	common ancestry; dispersal; evolution; genotype; hepatitis; human immunodeficiency virus; hunter-gatherer; infectious disease; Mesolithic; Neolithic; prehistoric; Eurasia; South America; Hepatitis B virus; Asia; Asian continental ancestry group; Caucasian; classification; communicable disease; Europe; genetic variation; genetics; genomics; hepatitis B; Hepatitis B virus; history; human; molecular evolution; paleontology; phylogeny; virology; Western Hemisphere; American Natives; Americas; Asia; Asian Continental Ancestry Group; Communicable Diseases, Emerging; Europe; European Continental Ancestry Group; Evolution, Molecular; Genetic Variation; Genomics; Hepatitis B; Hepatitis B virus; History, Ancient; Humans; Paleontology; Phylogeny
语种	英语
来源期刊	Science
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/244375
作者单位	Transmission, Max Planck Institute for Science of Human History, Germany; Department of Archaeogenetics, Max Planck Institute for Science of Human History, Germany; Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Germany; Max Planck Institute for Infection Biology, Germany; Archaeo- and Palaeogenetics Group, Eberhard Karls University Tübingen, Germany; Arc Centre of Excellence for Mathematical and Statistical Frontiers, School of Mathematical Sciences, University of Adelaide, Adelaide, SA 5005, Australia; Department of Medicine Ii, Leipzig University Medical Center, Germany; Department of Genetics, Harvard Medical School, Boston, MA, United States; Department of Human Evolutionary Biology, Harvard University, Cambridge, MA 02138, United States; Institute of Evolutionary Biology, CSIC-Universitat Pompeu Fabra, Barcelona, Spain; Université de Bordeaux, CNRS, Pacea Umr 5199, Pessac, France; Institute of Evolutionary Medicine (IEM), University of Zürich, Z rich, 8057, Swit...
推荐引用方式 GB/T 7714	Kocher A.,Papac L.,Barquera R.,et al. Ten millennia of hepatitis B virus evolution[J],2021,374(6564).
APA	Kocher A..,Papac L..,Barquera R..,Key F.M..,Spyrou M.A..,...&Kocher A..(2021).Ten millennia of hepatitis B virus evolution.Science,374(6564).
MLA	Kocher A.,et al."Ten millennia of hepatitis B virus evolution".Science 374.6564(2021).