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| DOI | 10.1126/science.1104635 |
| Systems biology and new technologies enable predictive and preventative medicine | |
| Hood L.; Heath J.R.; Phelps M.E.; Lin B. | |
| 发表日期 | 2004 |
| ISSN | 0036-8075 |
| 起始页码 | 640 |
| 结束页码 | 643 |
| 卷号 | 306期号:5696 |
| 英文摘要 | Systems approaches to disease are grounded in the idea that disease-perturbed protein and gene regulatory networks differ from their normal counterparts; we have been pursuing the possibility that these differences may be reflected by multiparameter measurements of the blood. Such concepts are transforming current diagnostic and therapeutic approaches to medicine and, together with new technologies, will enable a predictive and preventive medicine that will lead to personalized medicine. |
| 英文关键词 | Blood; Disease control; Genes; Parameter estimation; Proteins; Disease-perturbed protein; Gene regulatory networks; Multiparameter measurements; Medicine; medicine; biotechnology; gene control; gene expression; gene function; nanotechnology; preventive medicine; priority journal; prostate cancer; review; Biological Markers; Computational Biology; Databases, Nucleic Acid; Diagnosis; Disease; Disease Progression; Forecasting; Gene Expression; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Microfluidics; Nanotechnology; Preventive Medicine; Prostate; Prostatic Neoplasms; Systems Analysis; Systems Theory; Therapeutics |
| 语种 | 英语 |
| 来源期刊 | Science
 |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/244055 |
| 作者单位 | Institute for Systems Biology, Seattle, WA, United States; Department of Chemistry, California Institute of Technology, Pasadena, CA, United States; Dept. of Molec. and Med. Pharmacol., David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States |
| 推荐引用方式 GB/T 7714 | Hood L.,Heath J.R.,Phelps M.E.,et al. Systems biology and new technologies enable predictive and preventative medicine[J],2004,306(5696). |
| APA | Hood L.,Heath J.R.,Phelps M.E.,&Lin B..(2004).Systems biology and new technologies enable predictive and preventative medicine.Science,306(5696). |
| MLA | Hood L.,et al."Systems biology and new technologies enable predictive and preventative medicine".Science 306.5696(2004). |
| 条目包含的文件 | 条目无相关文件。 | |||||
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