气候变化领域集成服务门户(CCPortal): Probing the chiroptical response of a single molecule

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DOI	10.1126/science.1134231
	Probing the chiroptical response of a single molecule
	Hassey R.; Swain E.J.; Hammer N.I.; Venkataraman D.; Barnes M.D.
发表日期	2006
ISSN	0036-8075
起始页码	1437
结束页码	1439
卷号	314 期号:5804
英文摘要	Chirally sensitive measurement techniques have generally been restricted to bulk samples. Here, we report the observation of fluorescence-detected circular dichroism (FDCD) from single (bridged-triarylamine) helicene molecules by using an excitation wavelength (457 nanometers) in the vicinity of an electronic transition that shows circular dichroism in bulk samples. The distributions of dissymmetry (g) parameters by analysis of signals from pure M- and P-type diastereomers are almost perfect mirror images of one another, each spanning a range of both positive and negative values. In addition, we observe a well-defined structure in the histogram of dissymmetry parameters suggestive of specific molecular orientations at the polymer interface. These single-molecule results highlight strong intrinsic circular dichroism responses that can be obscured by cancellation effects in ensemble measurements of a randomly oriented bulk sample.
英文关键词	Amines; Fluorescence; Molecular orientation; Cancellation effects; Diastereomers; Intrinsic circular dichroism; Perfect mirror images; Molecular structure; aromatic amine; bridged compound; polymer; fluorescence; measurement method; molecular analysis; organic compound; probe; article; chirality; circular dichroism; diastereoisomer; fluorescence; histogram; measurement; optical rotation; priority journal; signal processing; technique
语种	英语
来源期刊	Science
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/243968
作者单位	Department of Chemistry, University of Massachusetts-Amherst, Amherst, MA 01003, United States
推荐引用方式 GB/T 7714	Hassey R.,Swain E.J.,Hammer N.I.,et al. Probing the chiroptical response of a single molecule[J],2006,314(5804).
APA	Hassey R.,Swain E.J.,Hammer N.I.,Venkataraman D.,&Barnes M.D..(2006).Probing the chiroptical response of a single molecule.Science,314(5804).
MLA	Hassey R.,et al."Probing the chiroptical response of a single molecule".Science 314.5804(2006).