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DOI	10.1126/science.aar7191
	Shifting the limits in wheat research and breeding using a fully annotated reference genome
	Appels R.; Eversole K.; Feuillet C.; Keller B.; Rogers J.; Stein N.; Pozniak C.J.; Choulet F.; Distelfeld A.; Poland J.; Ronen G.; Barad O.; Baruch K.; Keeble-Gagnère G.; Mascher M.; Ben-Zvi G.; Josselin A.-A.; Himmelbach A.; Balfourier F.; Gutierrez-Gonzalez J.; Hayden M.; Koh C.S.; Muehlbauer G.; Pasam R.K.; Paux E.; Rigault P.; Tibbits J.; Tiwari V.; Spannagl M.; Lang D.; Gundlach H.; Haberer G.; Mayer K.F.X.; Ormanbekova D.; Prade V.; Wicker T.; Swarbreck D.; Rimbert H.; Felder M.; Guilhot N.; Kaithakottil G.; Keilwagen J.; Leroy P.; Lux T.; Twardziok S.; Venturini L.; Juhasz A.; Abrouk M.; Fischer I.; Uauy C.; Borrill P.; Ramirez-Gonzalez R.H.; Arnaud D.; Chalabi S.; Chalhoub B.; Cory A.; Datla R.; Davey M.W.; Jacobs J.; Robinson S.J.; Steuernagel B.; Van Ex F.; Wulff B.B.H.; Benhamed M.; Bendahmane A.; Concia L.; Latrasse D.; Alaux M.; Bartoš J.; Bellec A.; Berges H.; Doležel J.; Frenkel Z.; Gill B.; Korol A.; Letellier T.; Olsen O.-A.; Šimková H.; Singh K.; Valárik M.; Van Der Vossen E.; Vautrin S.; Weining S.; Fahima T.; Glikson V.; Raats D.; Toegelová H.; Vrána J.; Sourdille P.; Darrier B.; Barabaschi D.; Cattivelli L.; Hernandez P.; Galvez S.; Budak H.; Jones J.D.G.; Witek K.; Yu G.; Small I.; Melonek J.; Zhou R.; Belova T.; Kanyuka K.; King R.; Nilsen K.; Walkowiak S.; Cuthbert R.; Knox R.; Wiebe K.; Xiang D.; Rohde A.; Golds T.; Čížkova J.; Akpinar B.A.; Biyiklioglu S.; Gao L.; N'Daiye A.; Číhalíková J.; Kubaláková M.; Šafář J.; Alfama F.; Adam-Blondon A.-F.; Flores R.; Guerche C.; Loaec M.; Quesneville H.; Sharpe A.G.; Condie J.; Ens J.; Maclachlan R.; Tan Y.; Alberti A.; Aury J.-M.; Barbe V.; Couloux A.; Cruaud C.; Labadie K.; Mangenot S.; Wincker P.; Kaur G.; Luo M.; Sehgal S.; Chhuneja P.; Gupta O.P.; Jindal S.; Kaur P.; Malik P.; Sharma P.; Yadav B.; Singh N.K.; Khurana J.P.; Chaudhary C.; Khurana P.; Kumar V.; Mahato A.; Mathur S.; Sevanthi A.; Sharma N.; Tomar R.S.; Holušová K.; Plíhal O.; Clark M.D.; Heavens D.; Kettleborough G.; Wright J.; Balcárková B.; Hu Y.; Ravin N.; Skryabin K.; Beletsky A.; Kadnikov V.; Mardanov A.; Nesterov M.; Rakitin A.; Sergeeva E.; Kanamori H.; Katagiri S.; Kobayashi F.; Nasuda S.; Tanaka T.; Wu J.; Cattonaro F.; Jiumeng M.; Kugler K.; Pfeifer M.; Sandve S.; Xun X.; Zhan B.; Batley J.; Bayer P.E.; Edwards D.; Hayashi S.; Tulpová Z.; Visendi P.; Cui L.; Du X.; Feng K.; Nie X.; Tong W.; Wang L.; International Wheat Genome Sequencing Consortium (IWGSC)
发表日期	2018
ISSN	0036-8075
卷号	361 期号:6403
英文摘要	An annotated reference sequence representing the hexaploid bread wheat genome in 21 pseudomolecules has been analyzed to identify the distribution and genomic context of coding and noncoding elements across the A, B, and D subgenomes. With an estimated coverage of 94% of the genome and containing 107,891 high-confidence gene models, this assembly enabled the discovery of tissue- and developmental stage-related coexpression networks by providing a transcriptome atlas representing major stages of wheat development. Dynamics of complex gene families involved in environmental adaptation and end-use quality were revealed at subgenome resolution and contextualized to known agronomic single-gene or quantitative trait loci. This community resource establishes the foundation for accelerating wheat research and application through improved understanding of wheat biology and genomics-assisted breeding. © 2017 The Authors.
英文关键词	transcriptome; transcriptome; breeding; gene expression; genome; genomics; research work; wheat; abiotic stress; Article; chromosome 21; controlled study; developmental stage; evolutionary adaptation; gene editing; gene expression; genetic trait; genetic transcription; genomics; hexaploidy; nonhuman; plant breeding; plant chromosome; plant gene; plant genome; priority journal; quantitative trait locus; sequence analysis; Triticum aestivum; wheat; anatomy and histology; book; bread; breeding; classification; gene expression regulation; genetics; growth, development and aging; molecular genetics; multigene family; phylogeny; standard; wheat; Triticum aestivum; Atlases as Topic; Bread; Breeding; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Genome, Plant; Molecular Sequence Annotation; Multigene Family; Phylogeny; Quantitative Trait Loci; Reference Standards; Transcriptome; Triticum
语种	英语
来源期刊	Science
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/242882
作者单位	AgriBio, Centre for AgriBioscience, Department of Economic Development, Jobs, Transport, and Resources, La Trobe University, 5 Ring Road, Bundoora, VIC 3083, Australia; International Wheat Genome Sequencing Consortium (IWGSC), 5207 Wyoming Road, Bethesda, MD 20816, United States; Eversole Assoc., 5207 Wyoming Road, Bethesda, MD 20816, United States; Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Genebank, Corrensstr. 3, Stadt Seeland, 06466, Germany; University of Western Australia (UWA), School of Agriculture and Environment, 35 Stirling Highway, Crawley, WA 6009, Australia; International Wheat Genome Sequencing Consortium (IWGSC), 18 High Street, Little Eversden, Cambridge, CB23 1HE, United Kingdom; GDEC (Genetics, Diversity and Ecophysiology of Cereals), INRA, Université Clermont Auvergne (UCA), 5 chemin de Beaulieu, Clermont-Ferrand, 63039, France; Institute of Experimental Botany, Centre of the Region Haná for Biotechnological and Agricultural Research, Šlechtitelù 31, Olomouc...
推荐引用方式 GB/T 7714	Appels R.,Eversole K.,Feuillet C.,et al. Shifting the limits in wheat research and breeding using a fully annotated reference genome[J],2018,361(6403).
APA	Appels R..,Eversole K..,Feuillet C..,Keller B..,Rogers J..,...&International Wheat Genome Sequencing Consortium .(2018).Shifting the limits in wheat research and breeding using a fully annotated reference genome.Science,361(6403).
MLA	Appels R.,et al."Shifting the limits in wheat research and breeding using a fully annotated reference genome".Science 361.6403(2018).