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DOI10.1073/pnas.2017947118
The human gut microbiome and health inequities
Amato K.R.; Arrieta M.-C.; Azad M.B.; Bailey M.T.; Broussard J.L.; Bruggeling C.E.; Claud E.C.; Costello E.K.; Davenport E.R.; Dutilh B.E.; Swain Ewald H.A.; Ewald P.; Hanlon E.C.; Julion W.; Keshavarzian A.; Maurice C.F.; Miller G.E.; Preidis G.A.; Segurel L.; Singer B.; Subramanian S.; Zhao L.; Kuzawa C.W.
发表日期2021
ISSN0027-8424
卷号118期号:25
英文摘要Individuals who are minoritized as a result of race, sexual identity, gender, or socioeconomic status experience a higher prevalence of many diseases. Understanding the biological processes that cause and maintain these socially driven health inequities is essential for addressing them. The gut microbiome is strongly shaped by host environments and affects host metabolic, immune, and neuroendocrine functions, making it an important pathway by which differences in experiences caused by social, political, and economic forces could contribute to health inequities. Nevertheless, few studies have directly integrated the gut microbiome into investigations of health inequities. Here, we argue that accounting for host–gut microbe interactions will improve understanding and management of health inequities, and that health policy must begin to consider the microbiome as an important pathway linking environments to population health. © 2021 National Academy of Sciences. All rights reserved.
英文关键词Structural racism|health disparities|chronic disease|DOHad|policy
语种英语
scopus关键词asthma; chronic disease; cognitive development; coronavirus disease 2019; disease course; health care policy; health disparity; host microbe interaction; human; intestine flora; malnutrition; mental disease; mental health; metabolic disorder; nerve cell differentiation; nonhuman; overnutrition; pandemic; population health; premature labor; racism; Review; social status; species composition
来源期刊Proceedings of the National Academy of Sciences of the United States of America
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/238887
作者单位Department of Anthropology, Northwestern University, Evanston, IL 60208, United States; Department of Physiology and Pharmacology, University of Calgary, Calgary, AB T2N 4N1, Canada; Department of Pediatrics, University of Calgary, Calgary, AB T2N 4N1, Canada; Children’s Hospital Research Institute of Manitoba, Winnipeg, MB R3E 3P4, Canada; Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB R3A 1S1, Canada; Center for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, OH 43205, United States; Department of Pediatrics, Ohio State University, Columbus, OH 43210, United States; Department of Health and Exercise Science, Colorado State University, Fort Collins, CO 80521, United States; Department of Pathology, Radboud University Medical Centre, Nijmegen, 6500 HB, Netherlands; Department of Pediatrics, University of Chicago, Chicago, IL 60637, United States; Department of Medicine, Stanford University School of Medicine, ...
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Amato K.R.,Arrieta M.-C.,Azad M.B.,et al. The human gut microbiome and health inequities[J],2021,118(25).
APA Amato K.R..,Arrieta M.-C..,Azad M.B..,Bailey M.T..,Broussard J.L..,...&Kuzawa C.W..(2021).The human gut microbiome and health inequities.Proceedings of the National Academy of Sciences of the United States of America,118(25).
MLA Amato K.R.,et al."The human gut microbiome and health inequities".Proceedings of the National Academy of Sciences of the United States of America 118.25(2021).
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