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DOI10.1073/pnas.2100201118
Quantifying COVID-19 importation risk in a dynamic network of domestic cities and international countries
Han X.; Xu Y.; Fan L.; Huang Y.; Xu M.; Gao S.
发表日期2021
ISSN0027-8424
卷号118期号:31
英文摘要Since its outbreak in December 2019, the novel coronavirus 2019 (COVID-19) has spread to 191 countries and caused millions of deaths. Many countries have experienced multiple epidemic waves and faced containment pressures from both domestic and international transmission. In this study, we conduct a multiscale geographic analysis of the spread of COVID-19 in a policy-influenced dynamic network to quantify COVID-19 importation risk under different policy scenarios using evidence from China. Our spatial dynamic panel data (SDPD) model explicitly distinguishes the effects of travel flows from the effects of transmissibility within cities, across cities, and across national borders. We find that within-city transmission was the dominant transmission mechanism in China at the beginning of the outbreak and that all domestic transmission mechanisms were muted or significantly weakened before importation posed a threat. We identify effective containment policies by matching the change points of domestic and importation transmissibility parameters to the timing of various interventions. Our simulations suggest that importation risk is limited when domestic transmission is under control, but that cumulative cases would have been almost 13 times higher if domestic transmissibility had resurged to its precontainment level after importation and 32 times higher if domestic transmissibility had remained at its precontainment level since the outbreak. Our findings provide practical insights into infectious disease containment and call for collaborative and coordinated global suppression efforts. © 2021 National Academy of Sciences. All rights reserved.
英文关键词COVID-19; Importation risk; Mobility networks; Spatial dynamic panel data model; Spatiotemporal analysis
语种英语
scopus关键词analytic method; Article; China; coronavirus disease 2019; disease transmission; geography; health care policy; human; intersectoral collaboration; population dynamics; protocol compliance; quantitative analysis; risk assessment; travel; city; communicable disease; communicable disease control; legislation and jurisprudence; prevention and control; risk; spatiotemporal analysis; statistical model; China; Cities; Communicable Disease Control; Communicable Diseases, Imported; COVID-19; Humans; Models, Statistical; Risk; SARS-CoV-2; Spatio-Temporal Analysis; Travel
来源期刊Proceedings of the National Academy of Sciences of the United States of America
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/238842
作者单位Wang Yanan Institute for Studies in Economics (WISE), Xiamen University, Xiamen, 361005, China; School of Economics, Xiamen University, Xiamen, 361005, China; Department of Agriculture and Consumer Economics, University of Illinois at Urbana-Champaign, Champaign, IL 61820, United States; Department of Agricultural Economics, Sociology, and Education, Pennsylvania State University, Philadelphia, PA 16802, United States; Institute of Urban Development, Nanjing Audit University, Nanjing, 211815, China; Geospatial Data Science Lab, Department of Geography, University of Wisconsin-Madison, Madison, WI 53706, United States
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GB/T 7714
Han X.,Xu Y.,Fan L.,et al. Quantifying COVID-19 importation risk in a dynamic network of domestic cities and international countries[J],2021,118(31).
APA Han X.,Xu Y.,Fan L.,Huang Y.,Xu M.,&Gao S..(2021).Quantifying COVID-19 importation risk in a dynamic network of domestic cities and international countries.Proceedings of the National Academy of Sciences of the United States of America,118(31).
MLA Han X.,et al."Quantifying COVID-19 importation risk in a dynamic network of domestic cities and international countries".Proceedings of the National Academy of Sciences of the United States of America 118.31(2021).
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