气候变化领域集成服务门户(CCPortal): Genomic basis of parallel adaptation varies with divergence in Arabidopsis and its relatives

CCPortal

DOI	10.1073/pnas.2022713118
	Genomic basis of parallel adaptation varies with divergence in Arabidopsis and its relatives
	Bohutínská M.; Vlček J.; Yair S.; Laenen B.; Konečná V.; Fracassetti M.; Slotte T.; Kolár F.
发表日期	2021
ISSN	0027-8424
卷号	118 期号:21
英文摘要	Parallel adaptation provides valuable insight into the predictability of evolutionary change through replicated natural experiments. A steadily increasing number of studies have demonstrated genomic parallelism, yet the magnitude of this parallelism varies depending on whether populations, species, or genera are compared. This led us to hypothesize that the magnitude of genomic parallelism scales with genetic divergence between lineages, but whether this is the case and the underlying evolutionary processes remain unknown. Here, we resequenced seven parallel lineages of two Arabidopsis species, which repeatedly adapted to challenging alpine environments. By combining genome-wide divergence scans with model-based approaches, we detected a suite of 151 genes that show parallel signatures of positive selection associated with alpine colonization, involved in response to cold, high radiation, short season, herbivores, and pathogens. We complemented these parallel candidates with published gene lists from five additional alpine Brassicaceae and tested our hypothesis on a broad scale spanning ∼0.02 to 18 My of divergence. Indeed, we found quantitatively variable genomic parallelism whose extent significantly decreased with increasing divergence between the compared lineages. We further modeled parallel evolution over the Arabidopsis candidate genes and showed that a decreasing probability of repeated selection on the same standing or introgressed alleles drives the observed pattern of divergence-dependent parallelism. We therefore conclude that genetic divergence between populations, species, and genera, affecting the pool of shared variants, is an important factor in the predictability of genome evolution. © 2021 National Academy of Sciences. All rights reserved.
英文关键词	alpine adaptation; Arabidopsis; evolution; Parallelism
语种	英语
scopus关键词	allele; Arabidopsis; article; cold stress; genetic variability; herbivore; human; infectious agent; nonhuman; probability; relative; season; genomics
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/238731
作者单位	Department of Botany, Faculty of Science, Charles University, Prague, 128 01, Czech Republic; Institute of Botany, Czech Academy of Sciences, Pruhonice, 252 43, Czech Republic; Biology Centre, Czech Academy of Sciences, Ceské Budejovice, 370 05, Czech Republic; Department of Zoology, Faculty of Science, University of South Bohemia, Ceské Budejovice, 370 05, Czech Republic; Center for Population Biology, University of California, Davis, CA 95616, United States; Department of Ecology, Environment and Plant Sciences, Science for Life Laboratory, Stockholm University, Stockholm, SE-106 91, Sweden
推荐引用方式 GB/T 7714	Bohutínská M.,Vlček J.,Yair S.,et al. Genomic basis of parallel adaptation varies with divergence in Arabidopsis and its relatives[J],2021,118(21).
APA	Bohutínská M..,Vlček J..,Yair S..,Laenen B..,Konečná V..,...&Kolár F..(2021).Genomic basis of parallel adaptation varies with divergence in Arabidopsis and its relatives.Proceedings of the National Academy of Sciences of the United States of America,118(21).
MLA	Bohutínská M.,et al."Genomic basis of parallel adaptation varies with divergence in Arabidopsis and its relatives".Proceedings of the National Academy of Sciences of the United States of America 118.21(2021).