气候变化领域集成服务门户(CCPortal): Assessing the origins of the european plagues following the black death: A synthesis of genomic, historical, and ecological information

CCPortal

DOI	10.1073/pnas.2101940118
	Assessing the origins of the european plagues following the black death: A synthesis of genomic, historical, and ecological information
	Bramanti B.; Wu Y.; Yang R.; Cui Y.; Stenseth N.C.
发表日期	2021
ISSN	0027-8424
卷号	118 期号:36
英文摘要	The second plague pandemic started in Europe with the Black Death in 1346 and lasted until the 19th century. Based on ancient DNA studies, there is a scientific disagreement over whether the bacterium, Yersinia pestis, came into Europe once (Hypothesis 1) or repeatedly over the following four centuries (Hypothesis 2). Here, we synthesize the most updated phylogeny together with historical, archeological, evolutionary, and ecological information. On the basis of this holistic view, we conclude that Hypothesis 2 is the most plausible. We also suggest that Y. pestis lineages might have developed attenuated virulence during transmission, which can explain the convergent evolutionary signals, including pla decay, that appeared at the end of the pandemics. © 2021 National Academy of Sciences. All rights reserved.
英文关键词	Black Death; Ecological epidemiology; European plague; Molecular evolution; Yersinia pestis
语种	英语
scopus关键词	bacterial gene; bacterial transmission; bacterial virulence; bubonic plague; cell lineage; Europe; evolutionary homology; gene synthesis; genomics; nonhuman; pandemic; phylogeny; pla gene; Review; Yersinia pestis
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/238651
作者单位	Centre for Ecological and Evolutionary Synthesis, Department of Biosciences, University of Oslo, Oslo, N-0316, Norway; Department of Neuroscience and Rehabilitation, Faculty of Medicine, Pharmacy and Prevention, University of Ferrara, Ferrara, 44121, Italy; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China; Ministry of Education Key Laboratory for Earth System Modeling, Department of Earth System Science, Tsinghua University, Beijing, 100084, China
推荐引用方式 GB/T 7714	Bramanti B.,Wu Y.,Yang R.,et al. Assessing the origins of the european plagues following the black death: A synthesis of genomic, historical, and ecological information[J],2021,118(36).
APA	Bramanti B.,Wu Y.,Yang R.,Cui Y.,&Stenseth N.C..(2021).Assessing the origins of the european plagues following the black death: A synthesis of genomic, historical, and ecological information.Proceedings of the National Academy of Sciences of the United States of America,118(36).
MLA	Bramanti B.,et al."Assessing the origins of the european plagues following the black death: A synthesis of genomic, historical, and ecological information".Proceedings of the National Academy of Sciences of the United States of America 118.36(2021).