气候变化领域集成服务门户(CCPortal): Comparative genomics provides insights into the aquatic adaptations of mammals

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DOI	10.1073/pnas.2106080118
	Comparative genomics provides insights into the aquatic adaptations of mammals
	Yuan Y.; Zhang Y.; Zhang P.; Liu C.; Wang J.; Gao H.; Rus Hoelzel A.; Seim I.; Lv M.; Lin M.; Dong L.; Gao H.; Yang Z.; Caruso F.; Lin W.; Da Fonseca R.R.; Wang D.; Wang X.; Rasmussen M.H.; Liu M.; Zheng J.; Zhao L.; Campos P.F.; Kang H.; Iversen M.; Song Y.; Guo X.; Guo J.; Qin Y.; Pan S.; Xu Q.; Meng L.; Yunga A.; Liu S.; Ming-Yuen Lee S.; Liu X.; Xu X.; Yang H.; Fan G.; Wang K.; Li S.
发表日期	2021
ISSN	0027-8424
卷号	118 期号:37
英文摘要	The ancestors of marine mammals once roamed the land and independently committed to an aquatic lifestyle. These macroevolutionary transitions have intrigued scientists for centuries. Here, we generated high-quality genome assemblies of 17 marine mammals (11 cetaceans and six pinnipeds), including eight assemblies at the chromosome level. Incorporating previously published data, we reconstructed the marine mammal phylogeny and population histories and identified numerous idiosyncratic and convergent genomic variations that possibly contributed to the transition from land to water in marine mammal lineages. Genes associated with the formation of blubber (NFIA), vascular development (SEMA3E), and heat production by brown adipose tissue (UCP1) had unique changes that may contribute to marine mammal thermoregulation. We also observed many lineage-specific changes in the marine mammals, including genes associated with deep diving and navigation. Our study advances understanding of the timing, pattern, and molecular changes associated with the evolution of mammalian lineages adapting to aquatic life. © 2021 National Academy of Sciences. All rights reserved.
英文关键词	Aquatic adaptation; Comparative genomics; Marine mammals
语种	英语
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/238644
作者单位	Marine Mammal and Marine Bioacoustics Laboratory, Institute of Deep-sea Science and Engineering, Chinese Academy of Sciences, Sanya, 572000, China; School of Ecology and Environment, Northwestern Polytechnical University, Xi'an, 710072, China; BGI-Qingdao, BGI-Shenzhen, Qingdao, 266555, China; BGI-Shenzhen, Shenzhen, 518083, China; Department of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, 2800, Denmark; State Key Laboratory of Agricultural Genomics, BGI-Shenzhen, Shenzhen, 518083, China; Department of Biosciences, Durham University, Durham, DH1 3LE, United Kingdom; Integrative Biology Laboratory, College of Life Sciences, Nanjing Normal University, Nanjing, 210046, China; School of Biology and Environmental Science, Queensland University of Technology, Brisbane, QLD 4000, Australia; Center for Macroecology, Evolution, and Climate, GLOBE Institute, University of Copenhagen, Copenhagen, 1165, Denmark; Key Laboratory of Aquatic Biodiversity and Conservation of Chinese Academy of ...
推荐引用方式 GB/T 7714	Yuan Y.,Zhang Y.,Zhang P.,et al. Comparative genomics provides insights into the aquatic adaptations of mammals[J],2021,118(37).
APA	Yuan Y..,Zhang Y..,Zhang P..,Liu C..,Wang J..,...&Li S..(2021).Comparative genomics provides insights into the aquatic adaptations of mammals.Proceedings of the National Academy of Sciences of the United States of America,118(37).
MLA	Yuan Y.,et al."Comparative genomics provides insights into the aquatic adaptations of mammals".Proceedings of the National Academy of Sciences of the United States of America 118.37(2021).