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DOI10.1073/pnas.2101314118
Discovery in space of ethanolamine, the simplest phospholipid head group
Rivilla V.M.; Jiménez-Serra I.; Martín-Pintado J.; Briones C.; Rodríguez-Almeida L.F.; Rico-Villas F.; Tercero B.; Zeng S.; Colzi L.; De Vicente P.; Martín S.; Requena-Torres M.A.
发表日期2021
ISSN0027-8424
卷号118期号:22
英文摘要Cell membranes are a key element of life because they keep the genetic material and metabolic machinery together. All present cell membranes are made of phospholipids, yet the nature of the first membranes and the origin of phospholipids are still under debate. We report here the presence of ethanolamine in space, NH2CH2CH2OH, which forms the hydrophilic head of the simplest and second-most-abundant phospholipid in membranes. The molecular column density of ethanolamine in interstellar space is N = (1.51 ± 0.07)×1013cm-2, implying a molecular abundance with respect to H2of (0:9-1:4)×10-10. Previous studies reported its presence in meteoritic material, but they suggested that it is synthesized in the meteorite itself by decomposition of amino acids. However, we find that the proportion of the molecule with respect to water in the interstellar medium is similar to the one found in the meteorite (10-6). These results indicate that ethanolamine forms efficiently in space and, if delivered onto early Earth, could have contributed to the assembling and early evolution of primitive membranes. © 2021 National Academy of Sciences. All rights reserved.
英文关键词Astrochemistry; Cell membranes; Ethanolamine; Molecular clouds; Prebiotic chemistry
语种英语
来源期刊Proceedings of the National Academy of Sciences of the United States of America
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/238539
作者单位Centro de Astrobiología, Consejo Sup. de Invest. Cientificas-Instituto Nacional de Tecnica Aeroespacial Esteban Terradas, Madrid, 28850, Spain; Osservatorio Astrofisico di Arcetri, Istituto Nazionale de Astrofisica, Florence, 50125, Italy; Observatorio Astronómico Nacional, Instituto Geográfico Nacional, Madrid, 28014, Spain; Star and Planet Formation Laboratory, Cluster for Pioneering Research, RIKEN, Wako, 351-0198, Japan; ALMA Department of Science, European Southern Observatory, Santiago, 763-0355, Chile; Department of Science Operations, Joint Atacama Large Millimeter/Submillimeter Array Observatory, Santiago, 763-0355, Chile; Department of Astronomy, University of Maryland, College Park, MD 20742, United States; Department of Physics, Astronomy and Geosciences, Towson University, Towson, MD 21252, United States
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Rivilla V.M.,Jiménez-Serra I.,Martín-Pintado J.,et al. Discovery in space of ethanolamine, the simplest phospholipid head group[J],2021,118(22).
APA Rivilla V.M..,Jiménez-Serra I..,Martín-Pintado J..,Briones C..,Rodríguez-Almeida L.F..,...&Requena-Torres M.A..(2021).Discovery in space of ethanolamine, the simplest phospholipid head group.Proceedings of the National Academy of Sciences of the United States of America,118(22).
MLA Rivilla V.M.,et al."Discovery in space of ethanolamine, the simplest phospholipid head group".Proceedings of the National Academy of Sciences of the United States of America 118.22(2021).
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