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DOI10.1073/pnas.2103126118
High-resolution multicontrast tomography with an x-ray microarray anode-structured target source
Zan G.; Gul S.; Zhang J.; Zhao W.; Lewis S.; Vine D.J.; Liu Y.; Pianetta P.; Yun W.
发表日期2021
ISSN0027-8424
卷号118期号:25
英文摘要Multicontrast X-ray imaging with high resolution and sensitivity using Talbot-Lau interferometry (TLI) offers unique imaging capabilities that are important to a wide range of applications, including the study of morphological features with different physical properties in biological specimens. The conventional X-ray TLI approach relies on an absorption grating to create an array of micrometer-sized X-ray sources, posing numerous limitations, including technical challenges associated with grating fabrication for high-energy operations. We overcome these limitations by developing a TLI system with a microarray anode-structured target (MAAST) source. The MAAST features an array of precisely controlled microstructured metal inserts embedded in a diamond substrate. Using this TLI system, tomography of a Drum fish tooth with high resolution and tri-contrast (absorption, phase, and scattering) reveals useful complementary structural information that is inaccessible otherwise. The results highlight the exceptional capability of high-resolution multicontrast X-ray tomography empowered by the MAAST-based TLI method in biomedical applications. © 2021 National Academy of Sciences. All rights reserved.
英文关键词Microarray anode-structured target; Phase-contrast tomography; Talbot-Lau grating interferometry; X-ray source
语种英语
来源期刊Proceedings of the National Academy of Sciences of the United States of America
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/238508
作者单位Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, United States; Sigray Inc., Concord, CA 94520, United States; School of Physics, Beihang University, Beijing, 100083, China
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GB/T 7714
Zan G.,Gul S.,Zhang J.,et al. High-resolution multicontrast tomography with an x-ray microarray anode-structured target source[J],2021,118(25).
APA Zan G..,Gul S..,Zhang J..,Zhao W..,Lewis S..,...&Yun W..(2021).High-resolution multicontrast tomography with an x-ray microarray anode-structured target source.Proceedings of the National Academy of Sciences of the United States of America,118(25).
MLA Zan G.,et al."High-resolution multicontrast tomography with an x-ray microarray anode-structured target source".Proceedings of the National Academy of Sciences of the United States of America 118.25(2021).
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