气候变化领域集成服务门户(CCPortal): Mechanism of the formation of proton transfer pathways in photosynthetic reaction centers

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DOI	10.1073/pnas.2103203118
	Mechanism of the formation of proton transfer pathways in photosynthetic reaction centers
	Sugo Y.; Saito K.; Ishikita H.
发表日期	2021
ISSN	0027-8424
卷号	118 期号:30
英文摘要	In photosynthetic reaction centers from purple bacteria (PbRCs) from Rhodobacter sphaeroides, the secondary quinone QB accepts two electrons and two protons via electron-coupled proton transfer (PT). Here, we identify PT pathways that proceed toward the QB binding site, using a quantum mechanical/molecular mechanical approach. As the first electron is transferred to QB, the formation of the Grotthuss-like pre-PT H-bond network is observed along Asp-L213, Ser-L223, and the distal QB carbonyl O site. As the second electron is transferred, the formation of a low-barrier H-bond is observed between His-L190 at Fe and the proximal QB carbonyl O site, which facilitates the second PT. As QBH2 leaves PbRC, a chain of water molecules connects protonated Glu-L212 and deprotonated His-L190 forms, which serves as a pathway for the His-L190 reprotonation. The findings of the second pathway, which does not involve Glu-L212, and the third pathway, which proceeds from Glu-L212 to His-L190, provide a mechanism for PT commonly used among PbRCs. © 2021 National Academy of Sciences. All rights reserved.
英文关键词	Artificial photosynthesis; Conformational gating; Low-barrier hydrogen bond; Photosystem II; Proton-coupled electron transfer
语种	英语
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/238457
作者单位	Department of Applied Chemistry, University of Tokyo, Tokyo, 113-8654, Japan; Research Center for Advanced Science and Technology, University of Tokyo, Tokyo, 153-8904, Japan
推荐引用方式 GB/T 7714	Sugo Y.,Saito K.,Ishikita H.. Mechanism of the formation of proton transfer pathways in photosynthetic reaction centers[J],2021,118(30).
APA	Sugo Y.,Saito K.,&Ishikita H..(2021).Mechanism of the formation of proton transfer pathways in photosynthetic reaction centers.Proceedings of the National Academy of Sciences of the United States of America,118(30).
MLA	Sugo Y.,et al."Mechanism of the formation of proton transfer pathways in photosynthetic reaction centers".Proceedings of the National Academy of Sciences of the United States of America 118.30(2021).